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Clinical Trials in Turkey / NCT07528677
Starting soon Observational

Ultrasound vs Clinical Parameters for Difficult Airway Prediction in Obesity

NCT07528677 · tracked via the Priya Life Science Turkey tracker
Phase
Observational
Started
2026-04-10
Last updated
2026-04-14

Condition(s) studied

Obesity (BMI > 35)Difficult AirwayDifficult Airway IntubationDifficult Mask Ventilation

Investigational drug(s) / intervention(s)

Airway Ultrasonography

Airway Ultrasonography: Preoperative airway ultrasonography will be performed by a trained anesthesiologist using a linear ultrasound probe with the patient in the supine position and head in neutral position. The following measurements will be obtained: (1) minimum distance from skin to hyoid bone (DSHB) at the transverse view of the hyoid bone level, (2) anterior neck soft tissue thickness at the thyrohyoid membrane level, and (3) hyomental distance ratio (HMDR), calculated as the ratio of hyomental distance in full extension (HMDe) to hyomental distance in neutral position (HMDn). These ultrasonographic parameters will be correlated with intraoperative Cormack-Lehane laryngoscopy grade and Han Scale mask ventilation score to assess their predictive value for difficult airway in obese patients.

Study summary

Obesity is associated with anatomical changes in the upper airway that increase the risk of difficult laryngoscopy and difficult mask ventilation during anesthesia. Conventional airway assessment parameters such as Mallampati score, neck circumference, and STOP-BANG scale are widely used but have limited predictive accuracy in obese patients. Airway ultrasonography has emerged as a promising non-invasive tool for difficult airway prediction; however, ultrasonographic criteria have not yet been standardized.

This prospective observational study aims to evaluate the utility of airway ultrasonography in predicting difficult airway in adult obese patients (BMI \>30 kg/m²) scheduled for elective surgery under general anesthesia. Ultrasonographic measurements will include the distance from skin to hyoid bone (DSHB) at the level of the hyoid bone, the anterior neck soft tissue thickness at the thyrohyoid membrane level, and the hyomental distance ratio (HMDR). These parameters will be compared with conventional airway assessment tools and correlated with intraoperative Cormack-Lehane laryngoscopy grade and Han Scale mask ventilation score to determine their predictive value for difficult airway.

Eligibility

Sex
ALL
Min age
18 Years
Max age
65 Years
Healthy volunteers
No
Inclusion Criteria: * Age 18-65 years * BMI \>30 kg/m2 * ASA physical status I, II, or III * Scheduled for elective surgery requiring orotracheal intubation under general anesthesia * Written informed consent obtained Exclusion Criteria: * Emergency surgery * History of previous head and neck surgery or radiotherapy * Known or anticipated difficult airway (history of difficult intubation) * Presence of cervical spine pathology or limited neck mobility * Presence of oropharyngeal or laryngeal pathology * Pregnancy * Patients with tracheostomy * Refusal to participate

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Fatih Sultan Mehmet Training and Research Hospital Istanbul Turkey (Türkiye)

More Fatih Sultan Mehmet Training and Research Hospital trials in Turkey

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07528677 on ClinicalTrials.gov ↗ ← All trials in Turkey