Relapsing Remitting Multiple Sclerosis (RRMS)Malnutrition or Risk of Malnutrition
Study summary
This prospective observational study aims to determine the prevalence of malnutrition in patients with relapsing-remitting multiple sclerosis and to evaluate its association with disability. Nutritional status will be assessed using the Mini Nutritional Assessment-Short Form, and body composition will be evaluated with bioelectrical impedance analysis and anthropometric measurements. The study will also assess urinary incontinence, depression, and anger-related features, and compare the findings with those of healthy controls.
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria:
* Age 18 years or older
* Diagnosis of relapsing-remitting multiple sclerosis for the patient group
* Absence of another medical condition that markedly impairs walking, such as severe cardiovascular disease, respiratory disease, or major orthopedic conditions
* Healthy volunteers willing to participate as controls
* Written informed consent provided
Exclusion Criteria:
* EDSS score ≥7 in the relapsing-remitting multiple sclerosis group
* Multiple sclerosis relapse during the last 30 days
* Systemic glucocorticoid treatment during the last 30 days
* History of musculoskeletal disease
* History of neuromuscular junction disease
Primary outcome measure(s)
Prevalence of malnutrition assessed by Mini Nutritional Assessment-Short Form — At baseline Malnutrition status and risk of malnutrition will be assessed using the Mini Nutritional Assessment-Short Form (MNA-SF) in patients with relapsing-remitting multiple sclerosis and healthy controls. MNA-SF is a screening tool with a total score ranging from 0 to 14. Lower scores indicate worse nutritional status. Scores from 12 to 14 indicate normal nutritional status, scores from 8 to 11 indicate risk of malnutrition, and scores from 0 to 7 indicate malnutrition.
The relationships between MNA-SF and anthropometric, body composition, depressive and anger-related variables will also be evaluated.
Trial sites (1)
Facility
City
Region
Status
Antalya Training and Research Hospital
Antalya
Antalya
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This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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