Effect Of Trendelenburg Position And Pneumoperitoneum On Optic Nerve Sheath Diameter In Robot-Assisted Prostatectomy

NCT07491198 · tracked via the Priya Life Science Turkey tracker

Sponsor

Ege University

Phase

Observational

Started

2026-01-05

Last updated

2026-09-10

Condition(s) studied

Prostate CancerOptic Nerve Sheath DiameterRobot-Assisted Radical ProstatectomySteep Trendelenburg Position With Penumoperitoneum in Robot Assisted Laparoscopic Prostatectomy

Study summary

This prospective study aims to evaluate the effect of steep Trendelenburg position and pneumoperitoneum on optic nerve sheath diameter in patients undergoing robot-assisted laparoscopic radical prostatectomy and open radical prostatectomy under general anesthesia. Increased intracranial pressure may occur during robotic surgery due to pneumoperitoneum and head-down positioning. Optic nerve sheath diameter measured by ocular ultrasonography is a non-invasive method used to assess intracranial pressure changes. Hemodynamic and respiratory parameters will also be recorded during surgery. The results of this study may help to better understand the physiological effects of surgical position and pneumoperitoneum during prostatectomy procedures.

Eligibility

Sex

MALE

Min age

18 Years

Max age

—

Healthy volunteers

Inclusion Criteria: * Age ≥ 18 years * ASA physical status I-III * Patients scheduled for robot-assisted laparoscopic radical prostatectomy or open radical prostatectomy under general anesthesia * Written informed consent obtained Exclusion Criteria: * History of intracranial surgery or intracranial lesion * Known ocular disease (glaucoma, retinal detachment, diabetic retinopathy, previous ocular surgery, etc.) * Intraocular pressure greater than 30 mmHg * Refusal to participate in the study

Primary outcome measure(s)

Optic Nerve Sheath Diameter — During surgery at predefined intraoperative time points
Measurement of optic nerve sheath diameter using ocular ultrasonography during surgery.

Trial sites (1)

Facility	City	Region	Status
Ege University Faculty of Medicine Hospital	Izmir	İzmir	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07491198 on ClinicalTrials.gov ↗ ← All trials in Turkey