Postoperative ComplicationsCritical IllnessInflammationIntensive Care Unit Admission
Study summary
This prospective observational cohort study aims to evaluate the predictive value of interleukin-6 (IL-6) levels and hemogram-derived inflammatory scores for morbidity and in-hospital mortality in postoperative patients admitted to the intensive care unit (ICU). IL-6 levels and inflammatory indices will be assessed at ICU admission and at 24 hours using data obtained from routine clinical care. Associations between these biomarkers and clinical outcomes, including mortality, morbidity, antibiotic use, and duration of mechanical ventilation, will be evaluated after adjustment for illness severity.
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
* Age ≥ 18 years
* Postoperative patients admitted to the ICU
* Availability of complete clinical and laboratory data at ICU admission and at 24 hours
* Provision of informed consent by the patient or legally authorized representative
Exclusion Criteria:
* Age \< 18 years
* Thoracic surgery patients
* Cardiac surgery patients
Primary outcome measure(s)
In-hospital mortality (all-cause) — Within 28 days of ICU admission In-hospital all-cause mortality within 28 days of intensive care unit admission, assessed using routinely collected clinical data.
Postoperative morbidity — Within 28 days Postoperative morbidity within 28 days of intensive care unit admission. Postoperative morbidity includes sepsis defined according to Sepsis-3 criteria and acute kidney injury defined according to KDIGO criteria, assessed using routinely collected clinical data.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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