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Clinical Trials in Turkey / NCT07432425
Recruiting Not applicable

Effects of Different Exercise Protocols on Physical and Cognitive Changes in People With Chronic Neck Pain

NCT07432425 · tracked via the Priya Life Science Turkey tracker
Phase
Not applicable
Started
2025-05-01
Last updated
2026-02-25

Condition(s) studied

Neck PainChronic Neck Pain

Investigational drug(s) / intervention(s)

Aerobic exerciseStrengthening exercisePosture and strentching exercise

Aerobic exercise: Participants will receive a total of 36 sessions of treatment, 3 sessions per week for 12 weeks. Aerobic exercise training will be performed with a bicycle ergometer, and a 5-minute warm-up (pedaling without resistance) program will be applied before the exercise training, finished by a 5-minute cool-down program (pedaling without resistance). Details of the intervention is described below: 60% of maximum heart rate, for 30 minutes (1-2nd weeks), 60% of maximum heart rate, for 45 minutes (3-4th weeks), 60% of maximum heart rate, for 60 minutes (5-6th weeks), mid-examination (at the end of the 6th week), 75% of maximum heart rate, for 30 minutes (7-8th weeks), 75% of maximum heart rate, for 45 minutes (9-10th weeks), 75% of maximum heart rate, for 60 minutes (11-12th weeks)

Strengthening exercise: A 5-minute warm-up (neck and upper extremity range of motion exercises) will be applied before the exercise training, and finished by a 5-minute cool-down program (neck and upper extremity range of motion exercises). Details of the intervention is described below: Isometric neck exercise (MVC 80%,2x10) and Theraband resistive neck and upper body exercises 10 RM-2x10 (1-2nd weeks), Isometric neck exercise (MVC 80%,3x10) and Theraband resistive neck and upper body exercises 10 RM-3x10 (3-4th weeks), Isometric neck exercise (MVC 80%,3x15) and Theraband resistive neck and upper body exercises 10 RM-3x15 (5-6th weeks) , mid-examination (6th week), Isometric neck exercise (MVC 80%,2x10) Theraband resistive neck and upper body exercises 10 RM-2x10 (7-8th weeks), Isometric neck exercise (MVC 80%,3x10) Theraband resistive neck and upper body exercises 10 RM-3x10 (9-10th weeks), Isometric neck exercise (MVC 80%,3x15) Theraband resistive neck and upper body exercises 10 RM-3x15 (11-12th weeks)

Posture and strentching exercise: Posture and stretching exercises and stretching exercises will be applied as a control treatment to volunteers with chronic neck pain included in the control group, and at the end of the study, these people will be included in the training program according to the exercise approach that is effective.

Study summary

This study aims to investigate the effects of different exercise approaches on physical status, cognitive functions, brain structures, and blood biomarkers in individuals with chronic neck pain.

Eligibility

Sex
ALL
Min age
20 Years
Max age
65 Years
Healthy volunteers
No
Inclusion Criteria: * Participants aged 20-65 * Having neck pain at least 3 months and rated as 3 or more according to the Numeric Rating Scale * Having a score of 10 or more according to the Neck Disability Index * Having a score of 24 or above according to the Mini Mental State Examination * Right hand dominancy according to Edinburgh Handedness Inventory * Having at least a primary school graduate Exclusion Criteria: * Having neuropsychiatric, neurologic, metabolic, cardiovascular, and inflammatory disease(s) * Participating in a rehabilitation program for neck pain in the last 6 months * Having an exercise or sports history of 6 months or more * Presence of brain parenchymal lesion on MRI * Presence of materials in the body such as jewelry, metal, hearing aid, pacemaker, lead that cannot be removed and are not suitable for MRI * History of neck or shoulder surgery * Being pregnant or having given birth within the last year

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Hacettepe University Faculty of Physical Therapy and Rehabilitation Ankara Altindag Recruiting

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Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07432425 on ClinicalTrials.gov ↗ ← All trials in Turkey