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Clinical Trials in Turkey / NCT07404813
Enrolling by invitation Not applicable

The Effect of Family Member Voices on Dopamine, Serotonin Levels, and Pain in Patients in Intensive Care Units

NCT07404813 · tracked via the Priya Life Science Turkey tracker
Sponsor
Zeliha CENGİZ
Phase
Not applicable
Started
2025-02-20
Last updated
2026-02-11

Condition(s) studied

Patient EngagementIntensive Care (ICU)Family Members' Voices

Investigational drug(s) / intervention(s)

Experimental Group

Experimental Group: The patients' relatives were given a detailed explanation of the procedures and were asked to fill out a patient/family satisfaction questionnaire. The topics to be discussed by the patient's family members were defined within a framework, and audio recordings were obtained. At 0 minutes, 5 mL of venous blood was drawn to assess dopamine and serotonin levels, and behavioral pain scores were recorded. Between 0 and 20 minutes, for 20 minutes, the audio recordings were played to the patient via headphones, 5 mL of venous blood was drawn again to assess dopamine and serotonin levels, and behavioral pain scores were recorded. At 10 minutes, the headphones were removed and the patient was exposed to normal ICU sounds. Between 30 and 50 minutes, again for 20 minutes, the audio recordings were played to the patient via headphones, 5 mL of venous blood was drawn again to assess dopamine and serotonin levels, and behavioral pain scores were recorded.

Study summary

In intensive care units, the frequent use of analgesics leads to polypharmacy and increased costs for patients. By embracing a patient-centered care principle, nursing believes that patients may be happier and experience reduced pain when they hear the voices of their familiar ones, thereby directly improving their quality of life. Listening to the voices of family members is expected to have positive effects on patients due to its ease of implementation, low cost, and non-invasive nature.

Eligibility

Sex
ALL
Min age
18 Years
Max age
65 Years
Healthy volunteers
No
Inclusion Criteria: * Must be between 18 and 65 years old. * Must be admitted to an intensive care unit (ICU). * Must not have been fed in the last hour. * Glasgow Coma Scale (GCS) score between 3 and 8. * To agitation in deep coma, the Richmond Agitation-Sedation Scale (RASS) score must be between -3 and +2. Exclusion Criteria: * Having a known hearing-related illness or having undergone a surgical procedure involving the ear. * Having taken any of the hormones cortisol, serotonin, or dopamine within the last 48 hours. * Having taken any analgesic within the last 4 hours.

Primary outcome measure(s)

Trial sites (2)

FacilityCityRegionStatus
Malatya Turgut Ozal Medical Center Malatya Malatya
Şırnak Üniversitesi Şırnak Merkez

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07404813 on ClinicalTrials.gov ↗ ← All trials in Turkey