One-lung ventilation is commonly used during thoracic surgery but is frequently associated with impaired oxygenation and altered respiratory mechanics. Traditional oxygenation indices require arterial blood gas analysis and do not fully reflect the mechanical stress applied to the lungs.
This prospective observational study aims to evaluate the correlation between oxygenation indices and oxygen saturation indices during one-lung ventilation in adult patients undergoing elective thoracic surgery. Modified indices incorporating driving pressure and mechanical power will also be assessed.
No intervention beyond standard clinical care will be applied. The findings of this study may help clarify the clinical utility of non-invasive oxygenation indices for intraoperative monitoring during one-lung ventilation.
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
* Patients aged 18 years and older
* Patients classified as ASA physical status I-III
* Patients scheduled for elective thoracic surgery requiring one-lung ventilation for at least 1 hour intraoperatively
* Patients in whom simultaneous arterial blood gas analysis and continuous SpO₂ monitoring can be performed
* Patients who have provided written informed consent
Exclusion Criteria:
* Patients undergoing emergency surgery
* Patients younger than 18 years of age
* Patients classified as ASA physical status IV or higher
* Patients with a history of previous thoracic surgery
* Patients with a body mass index (BMI) \>40 kg/m² or \<18 kg/m²
* Patients with advanced chronic lung disease (COPD stage III-IV)
* Patients with New York Heart Association (NYHA) class III-IV heart failure
* Patients undergoing surgery due to pleural effusion
Primary outcome measure(s)
Correlation between oxygenation indices and oxygen saturation indices — During intraoperative one-lung ventilation Correlation between invasive oxygenation indices (oxygenation index and its derivatives) and non-invasive oxygen saturation indices (oxygen saturation index and its derivatives) measured during one-lung ventilation.
Trial sites (1)
Facility
City
Region
Status
Ankara Ataturk Sanatoryum Education and Research Hospital
Ankara
Turkey (Türkiye)
More Ankara Ataturk Sanatorium Training and Research Hospital trials in Turkey
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
We use cookies to analyse site traffic and improve your experience. With your consent, we may also use cookies for advertising. You can change your choice at any time.