PENG Block & PENG PRF

NCT07360093 · tracked via the Priya Life Science Turkey tracker

Sponsor

Ankara City Hospital Bilkent

Phase

Observational

Started

2026-02-01

Last updated

2026-03-18

Condition(s) studied

Osteoarthritis (OA) of the Hip

Investigational drug(s) / intervention(s)

PENG Block Pulsed radiofrequency

PENG Block Pulsed radiofrequency: This intervention consists of a stepwise, two-stage treatment protocol routinely applied in our clinical practice for the management of chronic hip pain. In the first stage, all patients undergo an ultrasound-guided pericapsular nerve group (PENG) block as a diagnostic and therapeutic procedure. Pain intensity is assessed using the Visual Analog Scale (VAS) following the diagnostic block. Only patients who demonstrate a clinically meaningful response, defined as a reduction of 50% or greater in VAS scores, proceed to the second stage of the intervention. In the second stage, pulsed radiofrequency (PRF) treatment is applied to the same target region in addition to the PENG block, aiming to achieve longer-lasting analgesia through neuromodulation without tissue destruction.

Study summary

The primary aim of this study is to prospectively compare the effects of the pericapsular nerve group (PENG) block alone and the combination of PENG block with pulsed radiofrequency (PRF) on pain intensity in patients with chronic hip pain. As a secondary aim, the effects of both treatment modalities on hip function are intended to be evaluated using valid and reliable functional assessment scales. Through this study, it is aimed to demonstrate the clinical contribution of adding PRF to the PENG block and to identify a more effective and longer-lasting approach for the interventional treatment of chronic hip pain.

Eligibility

Sex

ALL

Min age

18 Years

Max age

80 Years

Healthy volunteers

Inclusion Criteria: * Presence of chronic hip pain lasting at least 3 months * Baseline Visual Analog Scale (VAS) score ≥ 4 * Clinical and/or radiological diagnosis of hip osteoarthritis * Inadequate response to conservative treatments Exclusion Criteria: * Local or systemic infection at the intervention site * Coagulopathy or inability to discontinue anticoagulant therapy * Hip pain related to malignancy * History of previous hip arthroplasty * Severe neurological deficit * Pregnancy or breastfeeding

Primary outcome measure(s)

Change in pain intensity measured by the Visual Analog Scale (VAS, 0-10; higher scores indicate worse pain) — baseline (pre-procedure) and at 1 week, 1 month, 3 months, and 6 months after the procedure.
Pain intensity will be assessed using the Visual Analog Scale (VAS), a validated pain measurement tool ranging from 0 to 10, where 0 indicates no pain and 10 represents the worst pain imaginable.

Trial sites (1)

Facility	City	Region	Status
Ankara Bilkent City Hospital	Ankara	Turkey (Türkiye)	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07360093 on ClinicalTrials.gov ↗ ← All trials in Turkey