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Clinical Trials in Turkey / NCT07074587
Completed Not applicable

Effects of Spinal Stabilization on the Pelvic Floor in Women With Multiple Sclerosis

NCT07074587 · tracked via the Priya Life Science Turkey tracker
Phase
Not applicable
Started
2025-06-30
Last updated
2026-09-28

Condition(s) studied

Multiple SclerosisUrinary IncontinenceLower Urinary Tract Symptoms

Investigational drug(s) / intervention(s)

Pelvic floor muscle exercisesSpinal stabilization exercises focusing on the pelvic floor + Pelvic floor muscle exercises

Pelvic floor muscle exercises: Pelvic floor muscle exercises will be taught with an innovative approach based on the principles of finding, feeling, forcing, following and functional training of the pelvic floor muscles. Pelvic floor muscle exercises will be applied as 3 sets in the first 2 weeks, 4 sets in the 3rd and 4th weeks, 5 sets in the 5th and 6th weeks, and finally 6 sets in the 7th and 8th weeks. Individuals will continue their pelvic floor muscle exercises as a home program.

Spinal stabilization exercises focusing on the pelvic floor + Pelvic floor muscle exercises: This program consists of 3 phases: 30 minutes of spinal stabilization exercises focusing on the pelvic floor, 5 minutes of warm-up and 5 minutes of cool-down exercises.The exercises will consist of 3 phases: static, dynamic and functional phases. Individuals will perform static phase exercises for the first 2 weeks, then dynamic phase exercises in the 3rd and 5th weeks and finally functional phase exercise in the 6th and 8th weeks. Individuals will be asked to maintain neutral spine position and abdominal bracing during pelvic floor muscle contraction during all exercises. Individuals will maintain the contraction for 5-10 seconds for 10 repetitions in each position in all phases.

Study summary

The purpose of this study was to investigate the effects of spinal stabilization exercises focusing on the pelvic floor on core stability, urinary symptoms and pelvic floor muscle function in women with Multiple Sclerosis and lower urinary tract symptoms. Participants will be randomly assigned to a control group that receives pelvic floor muscle exercises only or an experimental group that receives both pelvic floor muscle exercises and spinal stabilization exercise focused on the pelvic floor. Outcome measures will be assessed pre- and post-intervention using validated instruments.

Eligibility

Sex
FEMALE
Min age
18 Years
Max age
65 Years
Healthy volunteers
No
Inclusion Criteria: * Female participants aged between 18 and 65 years * Being diagnosed with Multiple Sclerosis by a specialist neurologist and having lower urinary system symptoms \[Overactive Bladder-V8 scale score ≥ 9 and having at least two of the lower urinary system symptoms (urinary incontinence, nocturia, daytime urination frequency \>8, storage symptoms such as sudden feeling of tightness, intermittent urination, slow urine flow and emptying symptoms such as incomplete emptying) * Being in the mild or moderate stage of the disease (Expanded Disability Status Scale (EDSS) score ˂ 6 * No relapse experienced within the past month * Scoring 24 or above on the Mini-Mental State Examination (MMSE) * Being literate * Willingness to voluntarily participate in the study * Ability to perform voluntary pelvic floor muscle contractions * No changes in medical treatment within the past three months * Ability to understand and cooperate with the assessments and interventions involved in the study Exclusion Criteria: * Diagnosis of one or more neurological disorders other than Multiple Sclerosis * Body mass index (BMI) ≥ 30 * Diagnosis of overflow urinary incontinence * History of antimuscarinic medication use * Presence of advanced pelvic organ prolapse (stage ≥ 2) * Active urinary tract infection * History of cesarean section or vaginal delivery within the past 6 months * Diagnosis of any other neurological condition that may cause urinary incontinence * History of urological or gynecological surgery * History of malignancy * Currently pregnant or not sexually active (coitus negative) * Participation in exercise training or physical therapy for lower urinary tract symptoms within the past 6 months

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Bolu Abant İzzet Baysal University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation Merkez Bolu

More Abant Izzet Baysal University trials in Turkey

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07074587 on ClinicalTrials.gov ↗ ← All trials in Turkey