Gram staining of the first urine after intraoperative renal puncture to predict the systemic inflammatory response after percutaneous nephrolithotomy.
Gram staining of the first urine after intraoperative renal puncture to predict the systemic inflammatory response after percutaneous nephrolithotomy.: Gram staining of the first urine after intraoperative renal puncture to predict the systemic inflammatory response after percutaneous nephrolithotomy.
Study summary
In this study, investigators compared the systemic inflammatory responses after percutaneous nephrolithotomy (PCNL) patients who were given an expanded empirical antibiotic regimen based on the prediction of the possibility of bacteria identified by Gram staining the first urine after renal puncture and patients whose antibiotic regimen was not performed and whose antibiotic regimen was adjusted according to patient symptoms and culture results. Investigators aimed to test its diagnostic value in predicting and preventing complications.
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
* patients with an indication for percutaneous nephrolithotomy due to kidney stone disease.
Exclusion Criteria:
* under 18 years old,
* having an active urinary tract infection before surgery and positive urine cultures,
* Patients with bilateral kidney stones,
* DJ stent or nephrostomy placement,
* Solitary kidney stones,
* Bleeding disorders,
* impaired kidney function,
* a history of antibiotic use for any reason within 2 weeks before randomization were excluded from the study.
Primary outcome measure(s)
Efficacy of Gram stain in predicting systemic inflammatory response after percutaneous nephrolithotomy. — immediately after the surgery Gram staining of urine after puncture to detect the presence of bacteria that are a possible source of infection according to the rate of gram-stained and non-gram-stained patients by microscopic examination.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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