Minimal Incision Surgery for median nerve decompressionUltrasound-guided perineural injection with 5 cc 5% Dextrose
Minimal Incision Surgery for median nerve decompression: Classic minimal incision surgical technique for median nerve decompression in patients diagnosed with mild, moderate, and severe carpal tunnel syndrome.
Ultrasound-guided perineural injection with 5 cc 5% Dextrose: The median nerve will be identified using ultrasound at the proximal entrance of the carpal tunnel. Using an ulnar approach with the in-plane technique, it was planned to inject 5 cc of 5% dextrose around the median nerve.
Study summary
The aim of this study is to compare ultrasound-guided perineural injection of the median nerve with classic minimal incision surgical technique for median nerve decompression in patients diagnosed with mild, moderate, and severe carpal tunnel syndrome.
Eligibility
Sex
ALL
Min age
18 Years
Max age
75 Years
Healthy volunteers
No
Inclusion Criteria:
* The presence of symptoms such as nocturnal, posture-related, or movement-related paresthesias, along with possible pain, in the area supplied by the median nerve in the hand, lasting for more than 3 months.
* Confirmation of mild, moderate or severe CTS through electrophysiological testing.
* Numbness and loss of sensation in the hand's regions innervated by the median nerve, as well as weakness in the thenar muscles innervated by the median nerve.
* Positive results on either the Phalen test and/or Tinel sign.
Exclusion Criteria:
* Individuals who may exhibit symptoms mimicking carpal tunnel syndrome, such as cervical radiculopathy, polyneuropathy, brachial plexopathy, or thoracic outlet syndrome.
* Patients who have received a previous injection into the carpal tunnel within the past 6 months.
* Thenar muscle atrophy.
* A history of prior carpal tunnel surgery.
* Regular usage of systemic nonsteroidal anti-inflammatory drugs and corticosteroids.
* Pregnancy
* Patients diagnosed with rheumatoid arthritis, systemic lupus erythematosus, gout, systemic sclerosis, dermatomyositis, or polymyositis.
* Malignancy.
* Active infections
Primary outcome measure(s)
Change from baseline visual analog scale (VAS) wrist pain at 4th and 12th week — baseline and 12th week Pain intensity was assessed using a visual analogue scale for pain, ranging from 0 to 10 mm, where 0 indicates the absence of pain and 10 signifies intense pain. This scale is widely recognized for its strong reliability and validity in measuring musculoskeletal pain.
Trial sites (1)
Facility
City
Region
Status
Afyonkarahisar Health Sciences University
Afyonkarahisar
Turkey (Türkiye)
Recruiting
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This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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