Effectiveness of Desensitisation and Pain Neuroscience Education in Patients With Carpal Tunnel Syndrome With Nosiplastic Pain

Condition(s) studied

Investigational drug(s) / intervention(s)

Desensitisation: This technique is utilized to decrease, or normalize, the body's response to particular sensations.

Pain neuroscience education: PNE is an educational intervention aiming to alter a patient's beliefs and cognitions regarding their pain experience.

Study summary

The aim of our study was to determine the effectiveness of desensitisation and pain neuroscience education in a group of patients with mixed phenotype pain (neuropathic and nosiplastic).

Eligibility

Primary outcome measure(s)

• Pressure Paın Threshold Measurement — [at the beginning of the study] [At the end of 6 weeks] [3 months later]
  The pressure pain threshold (PPT), the minimum amount of pressure at which the pressure sensation changes to pain, is measured with an electronic algometer (median nerve, ulnar nerve and radial nerve, C5-C6 zygapophyseal joint level (proximal), and tibialis anterior). Participants are asked to report when the sensation changes from pressure to pain. The mean of the three trials is calculated (with a 30 s rest interval in between).
• Boston Carpal Tunnel Questionnaire - Symptom Severity Scale — [at the beginning of the study] [At the end of 6 weeks] [3 months later]
  Boston Carpal Tunnel Questionnaire - Symptom Severity Scale is an 11-item questionnaire used to assess symptom severity in individuals with CTS. Each item is scored from 1 to 5. Scores range from 1 (no symptoms) to 5 (worst symptoms). The patient's symptom severity score is the average score of 11 items.
• Boston Carpal Tunnel Questionnaire - Functional Status Scale — [at the beginning of the study] [At the end of 6 weeks] [3 months later]
  Boston Carpal Tunnel Questionnaire - Functional Status Scale is an 8-item questionnaire used to assess the functional status of patients with CTS. Each item is scored from 1 to 5. Scores range from 1 (no functional deficit) to 5 (worst possible function). The patient's functional status score is the average of all 8 items.
• Pain Catastrophising Scale — [at the beginning of the study] [At the end of 6 weeks] [3 months later]
  The Catastrophising Pain Scale (PCS) is used to measure catastrophising in response to pain through 13 statements with four possible options from 1 "never" to 4 "always". Higher scores indicate greater catastrophised pain.
• Tampa Kinesiophobia Scale — [at the beginning of the study] [At the end of 6 weeks] [3 months later]
  It is a 17-question scale. The scale has a 4-point Likert scale (1= Strongly disagree, 4= Strongly agree). After reversing items 4, 8, 12 and 16, a total score is calculated. The person receives a total score between 17-68. A high score on the scale indicates a high level of kinesiophobia.
• Numerical Rating Scale — [at the beginning of the study] [At the end of 6 weeks] [3 months later]
  Patients rate the current pain intensity from 0 ("no pain") to 10 ("worst possible pain").

Trial sites (1)

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