Peripheral pULSe Assessment and Arterial pRessure (PULSAR)

Condition(s) studied

Investigational drug(s) / intervention(s)

Peripheral Pulse Palpation: Manual palpation of carotid, femoral, and radial pulses performed during routine clinical care in patients with circulatory instability. Simultaneous arterial blood pressure measurements are recorded from standard monitoring systems. No study-specific treatment or intervention is administered.

Study summary

This prospective multicenter observational study aims to investigate the relationship between palpable peripheral pulses and simultaneously measured arterial blood pressure in adult patients with circulatory shock or impending circulatory failure. Peripheral pulse palpation is routinely used in emergency medicine, trauma care, critical care, and cardiopulmonary resuscitation as a rapid clinical assessment of circulation. However, the association between palpable pulses and actual arterial blood pressure remains poorly validated.

Patients treated in emergency departments, intensive care units, operating rooms, and other acute care settings will undergo routine pulse palpation at predefined anatomical locations including carotid, femoral, and radial arteries. Simultaneously measured non-invasive and/or invasive arterial blood pressure values will be recorded from routine clinical monitoring systems. Additional clinical variables relevant to circulatory status will also be collected.

The study seeks to define blood pressure thresholds associated with pulse palpability and evaluate the agreement between invasive and non-invasive blood pressure measurements in patients with circulatory shock.

Eligibility

Primary outcome measure(s)

• Association between palpable pulses and systolic arterial blood pressure — During episodes of circulatory instability, up to 24 hours after inclusion
  Relationship between palpable carotid, femoral, and radial pulses and simultaneously measured systolic arterial blood pressure.

Trial sites (1)

More Region Stockholm trials in Sweden

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