Effects of Fibres Combined With Probiotics on Uric Acid in an ex Vivo Fermentation Model

Inclusion Criteria: 1. Signed informed consent prior to any study-related procedures 2. Age 18-80 years old 3. BMI range 18.5-35 kg/m2 4. Blood uric acid above 0.36 mmol/L (6 mg/dl) 5. Willing to abstain from regular consumption of probiotic supplements or food products containing probiotic bacteria (including fermented food and beverages), until collection of faecal material 6. Willing to abstain from regular consumption of supplements and medications known to alter gastrointestinal function or inflammatory status during the study, until collection of faecal material Exclusion Criteria: 1. Diagnosis of type 1 and/or type 2 diabetes 2. Diagnosed inflammatory bowel disease (IBD) 3. Current diagnosis of psychiatric disease/s or syndromes 4. Current diagnosis of neurodegenerative disease 5. Current pregnancy or breastfeeding 6. History of complicated gastrointestinal surgery 7. Systemic use of antibiotics and/or steroid medication in the last 4 months prior to inclusion 8. Regular use of any non-steroidal anti-inflammatory drug (NSAID) for the last 2 months 9. Consumption of any NSAID within 3 days of sample collection 10. Current (or within the last 4 weeks prior to study start) use of probiotic supplementation 11. Any condition or intake of medication which could substantially interfere with the outcome of the study, as decided by the principal investigator's discretion 12. After being included in the study and until collection of faecal material, starting any medication or treatment that could potentially influence the study participation and/or study analysis