Multicomponent Training and Muscle Quality in Older Women

Condition(s) studied

Investigational drug(s) / intervention(s)

Multicomponent training: The exercise battery includes lower body work (squats, deadlifts, front and sagittal plane lunges, hip abduction/extension, and plantar flexion) and upper body work (wall flexion-extensions, shoulder raises, and elbow flexion-extensions). In addition to the strength exercises mentioned above, balance exercises such as walking in tandem, standing on one leg, side steps, and weight transfer will also be performed. Aerobic capacity will be worked on by walking at a moderate intensity, and flexibility will be improved through stretching the main muscle groups.

Study summary

This study aims to evlauate the effect os a 32-week multicomponent training (MT) program on muscle architecture and muscle quality (assessed by ultrasound) in womer over 60 years. The study will also analyze concurrent changes in muscle strength, physical performance, and body composition. The hypothesis is that the training will induce positive architectural adaptations, such as reduced echogenicity and increased thickness in the rectus femoris and rectus abdominis muscles, correlating with improved functional independence.

Eligibility

Primary outcome measure(s)

• Echo intensity — Baseline and 32 weeks
  Echo intensity (gray scale analysis), using ImageJ software, proposed by the SARCUS consensus and Nutritional Ultrasound ®.
• Muscle thickness (mm) — Baseline and 32 weeks
  Linear measurement of the distance between the superficial and deep aponeuroses of a target muscle belly.
• Cross-sectional area — Baseline and 32 weeks
  The total area of the muscle (measured in cm\^2) in a plane perpendicular to its longitudinal axis
• Subcutaneous adipose tissue thickness — Baseline and 32 weeks
  Measurement of the distance between the dermis and the superficial muscle fascia. This variable quantifies the thickness of the fat layer located directly beneath the skin.

Trial sites (1)

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