Value of Screening and Treatment of SAHS in the Management of AF Ablation Candidates

NCT04606693 · tracked via the Priya Life Science Spain tracker

Sponsor

Hospital San Carlos, Madrid

Phase

Not applicable

Started

2020-11-05

Last updated

2025-09-15

Condition(s) studied

Atrial Fibrillation ParoxysmalAtrial Fibrillation, PersistentApnea SyndromeHypopnea Syndrome

Investigational drug(s) / intervention(s)

Treatment of SAHS

Treatment of SAHS: Patients diagnosed with SAHS will be treated in the Pneumology Service according to usual practice (dietary hygienic measures, CPAP, etc.).

Study summary

The present prospective cohort study (not randomized) analyses the value of screening and treatment of SAHS in the management of patients with AF refractory to antiarrhythmics drugs, potentially candidates for ablation.

Patients at low risk of suffering from SAHS will follow conventional management of their AF, according to the usual criteria of the Arrhythmia Unit. Patients with high or intermediate risk of SAHS, will undergo respiratory polygraphy. If the result is positive, they will be treated as standard for this syndrome and their heart rate will be monitored for 3 months. After this, the patient's arrhythmic load will be reevaluated differentiating patients into two groups, those that must be ablated from those that have improved their condition and the clinical criteria is no longer ablation but follow-up.

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Inclusion Criteria: * Patients with paroxysmal or persistent atrial fibrillation * Recurrent atrial fibrillation despite treatment with at least one class I or III antiarrhythmic * No previous diagnosis of apnea-hypopnea syndrome Exclusion Criteria: * Patients \<18 years * Pregnant women * Doubts about the patient's ability to perform a home respiratory polygraphy * Doubts about the patient's ability to acquire rhythm records with the Kardia system (smartphone required) * Unavailability for follow-up at our center for at least 1 year.

Primary outcome measure(s)

Arrhythmic load — Six months
Rate of time in FA measured with Kardia © recorder

Trial sites (1)

Facility	City	Region	Status
Hospital Clínico San Carlos	Madrid	Madrid	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT04606693 on ClinicalTrials.gov ↗ ← All trials in Spain