🇮🇪Ireland
16°C Partly Cloudy · Dublin
Live Updates
--:--:-- IST
Contributor sign in
Latest
Clinical Trials in South Korea / NCT07018323
Recruiting Phase 2

A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease

NCT07018323 · tracked via the Priya Life Science South Korea tracker
Phase
Phase 2
Started
2025-06-19
Last updated
2026-08-25

Condition(s) studied

Graves' Disease

Investigational drug(s) / intervention(s)

IMVT-1402 →IMVT-1402 →Placebo

IMVT-1402: Dose 1 for 26 weeks

IMVT-1402: Dose 2 for 26 weeks

Placebo: For 26 weeks

Study summary

This is a multi-center, global, randomized, double-blind, placebo-controlled Phase 2b study to assess the efficacy, safety, and tolerability of IMVT-1402 in adult participants with Graves' disease (GD) who are hyperthyroid despite antithyroid drug (ATD) treatment.

Eligibility

Sex
ALL
Min age
18 Years
Max age
75 Years
Healthy volunteers
No
Inclusion Criteria: * Participants with the ability to understand the requirements of the trial, provide written informed consent, and comply with the trial protocol procedures. * Male or female participants aged ≥ 18 years. * Participants with diagnosis of GD who are hyperthyroid despite ATD treatment. * Other, more specific inclusion criteria are defined in the protocol. Exclusion Criteria: * Have previously been successfully treated with radioactive iodine (RAI) therapy or have undergone total thyroidectomy. * Have an autoimmune disease other than GD requiring treatment that, in the Investigator's judgment, puts the participant at undue risk. * Have moderate-to-severe active thyroid eye disease (TED) and are expected to require immediate surgical intervention and/or are planning corrective surgery/irradiation or medical therapy for TED during study participation. * Additional exclusion criteria are defined in the protocol.

Primary outcome measure(s)

Trial sites (163)

FacilityCityRegionStatus
Site Number - 1015 Tucson Arizona Recruiting
Site Number -1014 Concord California Recruiting
Site Number - 1013 Aurora Colorado Recruiting
Site Number - 1024 Doral Florida Recruiting
Site Number - 1008 Hialeah Florida Recruiting
Site Number - 1000 Miami Florida Recruiting
Site Number - 1020 Columbus Georgia Recruiting
Site Number - 1022 Topeka Kansas Recruiting
Site Number - 1030 Louisville Kentucky Recruiting
Site Number - 1033 Jefferson City Missouri Recruiting
Site Number - 1004 Kansas City Missouri Recruiting
Site Number - 1019 St Louis Missouri Recruiting
Site Number - 1012 Reno Nevada Recruiting
Site Number - 1032 Long Island City New York Recruiting
Site Number - 1027 New Hyde Park New York Recruiting
Site Number - 1009 New York New York Recruiting
Site Number - 1018 Williamsville New York Recruiting
Site Number - 1010 Chapel Hill North Carolina Recruiting
Site Number - 1026 Hickory North Carolina Recruiting
Site Number - 1001 Morehead City North Carolina Recruiting
Site Number - 1034 Raleigh North Carolina Recruiting
Site Number - 1007 Oklahoma City Oklahoma Recruiting
Site Number - 1017 Memphis Tennessee Recruiting
Site Number - 1029 Dallas Texas Recruiting
Site Number - 1002 El Paso Texas Recruiting
Site Number - 1003 Fort Worth Texas Recruiting
Site Number - 1031 Houston Texas Recruiting
Site Number - 1028 Houston Texas Recruiting
Site Number -1023 Irving Texas Recruiting
Site Number - 1021 Irving Texas Recruiting
Site Number - 1025 McKinney Texas Recruiting
Site Number - 1011 San Antonio Texas Recruiting
Site Number - 1016 Norfolk Virginia Recruiting
Site Number - 5105 Sydney New South Wales Recruiting
Site Number - 5103 Warrawong New South Wales Recruiting
Site Number - 5101 Brisbane Queensland Recruiting
Site Number - 5107 Douglas Queensland Recruiting
Site Number - 5100 Southport Queensland Recruiting
Site Number - 5102 Box Hill Victoria Recruiting
Site Number - 5104 Geelong Victoria Recruiting

+ 123 more sites — see the full list on the official registry below.

More Immunovant Sciences GmbH trials in South Korea

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07018323 on ClinicalTrials.gov ↗ ← All trials in South Korea