Patients admitted to the cardiology department with acute heart failure who have a nasopharyngeal respiratory virus PCR test performed within 72 hours of admission will be enrolled in the study cohort.
The detection rate of respiratory viruses including influenza virus, RSV, and coronavirus will be analysed. The investigators will also look for seasonal changes in the frequency of respiratory viruses and differences in the clinical presentation of heart failure based on respiratory virus infection.
Eligibility
Sex
ALL
Min age
19 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
* Adult aged 19 years or older admitted to the cardiology department with acute heart failure
* NT-proBNP \>300 pg/mL
* Clinician judgement of possible respiratory viral infection (fever \>38 degrees or cough, respiratory symptoms such as sputum or consolidation on x-ray or CRP \>5 mg/dL)
* Patients who have a nasopharyngeal swab for respiratory virus PCR test performed within 72 hours of admission for any of the 3 reasons
Exclusion Criteria:
* Patients with a clear other cause of acute heart failure (ex. ACS, bradycardia requiring a pacemaker, uncontrolled tachycardia, uncontrolled severe hypertension (SBP \>180mmHg or DBP \>110mmHg), haemoglobin \<7g/dL or AHF precipitated by medication non-adherence)
* If the cause of pulmonary oedema is prominently attributed to exacerbation of CKD
* If there is a clear other source of infection that can explain the fever
Primary outcome measure(s)
Respiratory virus PCR detection rate — Within 3 days of admission Respiratory virus PCR detection rate (especially RSV, influenza virus) in acute HF
Trial sites (3)
Facility
City
Region
Status
Seoul National University Bundang Hospital
Seongnam-si
Gyeonggi-do
Recruiting
Samsung medical center
Seoul
South Korea
Recruiting
Seoul ST. Mary's Hospital
Seoul
South Korea
Recruiting
Official registry record
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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