Primary Stability and Peri-implant Outcomes of Short Implants in Post-extraction Single-tooth Sites

NCT07177521 · tracked via the Priya Life Science Italy tracker

Sponsor

University of Bari Aldo Moro

Phase

Not applicable

Started

2025-01-10

Last updated

2026-01-27

Condition(s) studied

Edentulous JawTooth LossToothless Mouth

Investigational drug(s) / intervention(s)

Insertion of implants in post-extraction tooth

Insertion of implants in post-extraction tooth: Two widely used approaches include: 1. Socket grafting with a fully resorbable synthetic biomaterial (β-tricalcium phosphate + calcium sulfate). 2. Socket grafting with a xenograft and a custom Sealing Socket Abutment (SSA) with a concave emergence profile. No randomized controlled trials have yet compared these protocols with integrated outcomes including resonance frequency analysis, peri-implant health indices, radiographic bone level changes, and digital intraoral scanning (IOS)-based morphometric analysis.

Study summary

The placement of short implants in post-extraction sockets is a valuable option when residual bone height is limited, minimizing morbidity and treatment time. The management of the peri-implant gap and soft tissues may influence primary stability, hard/soft tissue remodeling, and implant success.

Eligibility

Sex

ALL

Min age

18 Years

Max age

75 Years

Healthy volunteers

Accepted

Inclusion Criteria: * Age ≥18 years. * Single-tooth post-extraction sites requiring immediate implant placement in posterior regions (premolars/molars) or selected anterior sites. * Planned short implant (≤7-8 mm length, 3.5-5.0 mm diameter). * Adequate oral hygiene, no active periodontal disease. * Written informed consent. Exclusion Criteria: * Heavy smoking (\>20 cigarettes/day). * Uncontrolled diabetes or systemic conditions affecting bone healing. * Current bisphosphonate/antiresorptive therapy. * Immunosuppression, pregnancy. * Poor oral hygiene or acute infection at site. * Severe bone dehiscence preventing primary stability.

Primary outcome measure(s)

Primary stability — 1 month
To compare the primary stability (ISQ values at implant insertion) of short implants placed in post-extraction sockets using the two grafting protocols.

Trial sites (1)

Facility	City	Region	Status
University of Bari Aldo Moro	Bari	Italy	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07177521 on ClinicalTrials.gov ↗ ← All trials in Italy