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Clinical trial register · Ireland

Clinical Trials in Limerick

Every study on the ClinicalTrials.gov registry that lists a site in Ireland and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 615 matching records held by the registry are in this view. Synced 22 Sep 2026, 03:15 UTC
615
Studies in scope
all four open statuses
323
Recruiting now
open to new participants
181
Lead sponsors
across recruiting studies
37
Irish site locations
across all listed studies
Phase mix of the 323 recruiting studies
Phase 3 98 Not applicable 79 Observational 76 Phase 2 30 Phase 1/2 20 Other 20
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Matches title, registry number, sponsor, intervention and condition.
Recruitment status
Phase
Lead sponsor
University of Limerick 10 Royal College of Surgeons, Ireland 4 Cancer Trials Ireland 3 Merck Sharp & Dohme LLC 3 National Cancer Institute (NCI) 2
Site location
Dublin 483 Cork 170 Galway 124 Limerick 56 Waterford 51
All 37 locations
Target enrolment
to
56 of 615 studies
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Status
Study
Lead sponsor
Phase
Enrol
Irish sites
Start
Recruiting
Optimising Adjuvant Chemotherapy Prescription in Young Patients With Hormone-dependent Breast Cancer Using Genomic Tests
NCT07106632 Early Breast Cancer, Premenopausal Breast Cancer, HR+/HER2- Breast Cancer
UNICANCER
Phase 3
3,380
Cork, Dublin, Limerick, Tullamore, Waterford
2026-06-26
Recruiting
Glycolytic Phenotype (vLapeak) and Magnitude of Skeletal Muscle Hypertrophy After Resistance Training
NCT07721766 Healthy Volunteers, Muscle Hypertrophy, Glycolysis, Moderately Trainend
Technical University of Munich
Not applicable
120
Limerick
2026-05-04
Recruiting
Frailty in Older Adults With Prostate Cancer: a Prospective Cohort Study
NCT07605936 Frailty at Older Adults, Prostate Cancer
University of Limerick
Observational
80
Limerick
2026-04-23
Recruiting
Profiling Patients With Rotator Cuff Related Shoulder Pain: What Factors Influence Outcomes With Non-operative Care in a Secondary Care Specialist Shoulder Clinic?
NCT07360847 Rotator Cuff Related Shoulder Pain, RCRSP
University of Limerick
Observational
150
Limerick
2026-01-05
Recruiting
A Study to Learn How Safe and How Well Linvoseltamab Works Compared to Standard Treatment in Adult Patients With Multiple Myeloma Who Are Not Eligible for Transplant
NCT06932562 Multiple Myeloma
European Myeloma Network B.V.
Phase 3
1,000
Cork, Dublin, Limerick
2025-12-23
Recruiting
A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
NCT06943872 Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
BeOne Medicines
Phase 3
630
Dublin, Galway, Limerick
2025-06-11
Recruiting
A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions
NCT06499285 Myelodysplastic Syndromes
Takeda
Phase 3
225
Cork, Dublin, Limerick
2025-05-06
Recruiting
A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)
NCT06890884 Lymphoma, Large B-Cell, Diffuse
Merck Sharp & Dohme LLC
Phase 2
594
Dublin, Limerick
2025-04-11
Recruiting
Inpatient Post-Acute Rehabilitation For Patients in the Midwest: a Prospective Cohort Study of Clinical Characteristics and Process Outcomes
NCT07351526 Rehabilitation, Frailty, Complex Patients in Rehabilitation Phase
University of Limerick
Observational
100
Limerick
2025-02-22
Recruiting
A Prospective Cohort Study of Clinical and Process Outcomes of Older Adults That Transition Through the Geriatric Emergency Medicine Unit(GEM-U)
NCT07237334 Frailty
University of Limerick
Observational
150
Limerick
2025-02-10
Active, closed
A Real-World Study to Gain Clinical Insights Into Faricimab (FaReal Study)
NCT06680817 Neovascular Age-related Macular Degeneration, Diabetic Macular Edema
Hoffmann-La Roche
Observational
850
Dublin, Limerick, Waterford
2025-02-05
Not yet open
Burnout and Resilience in Hospital-based Nursing and Medical Personnel and Trainees
NCT06818539 Stress, Burnout
University of Limerick
Observational
650
Limerick
2025-02-01
By invitation
PIECES - Towards Large-Scale Adaptation and Tailored Implementation of Primary Cancer Prevention Programs
NCT06718322 Focus of Study: Tailored Implementation
Hidde van der Ploeg
Not applicable
100
Limerick
2024-12-01
Active, closed
Trial to Evaluate Acasunlimab and Pembrolizumab Combination Superiority Over Standard of Care Docetaxel in Non-Small Cell Lung Cancer (ABBIL1TY NSCLC-06)
NCT06635824 PD-L1-positive, Locally Advanced (Unresectable Stage IIIB/C) or Metastatic NSCLC
Genmab
Phase 3
191
Cork, Dublin, Limerick, Waterford
2024-11-25
Recruiting
ENVELOP: Wound Care Following Pilonidal Sinus Surgery
NCT06647290 Pilonidal Sinus, Wound Healing
Royal College of Surgeons, Ireland
Not applicable
200
Dublin, Castlebar, Kilkenny, Limerick, Tullamore, Waterford
2024-10-01
Recruiting
Community-based Exercise for Older Adults With Chronic Musculoskeletal Pain
NCT06535633 Chronic Musculoskeletal Pain
University of Limerick
Not applicable
72
Limerick
2024-09-01
Recruiting
PINTA - Prophylactic Incisional Negative Pressure Therapy for Major Amputations
NCT06025253 Wound Surgical, Wound Infection, Cosmesis
Royal College of Surgeons, Ireland
Not applicable
728
Dublin, Galway, Limerick, Waterford
2024-03-01
Active, closed
The Impact of Domiciliary Versus 'Hub' Based Comprehensive Geriatric Assessment on Clinical and Process Outcomes Among Older Adults Attending Community Specialist Teams: a Randomised Controlled Trial.
NCT06205238 Frailty, Comprehensive Geriatric Assessment, Older Adults, Domiciliary Care
University of Limerick
Not applicable
106
Limerick
2024-01-15
Recruiting
Occupational Therapy-led Services for Adults Presenting Acutely With a Hand Condition
NCT06399614 Hand Injuries
University of Limerick
Observational
150
Dublin, Galway, Limerick, Tipperary
2024-01-11
Active, closed
Neoadjuvant Trastuzumab Deruxtecan (T-DXd) With Response-directed Definitive Therapy in Early Stage HER2-positive Breast Cancer (SHAMROCK Study)
NCT05710666 HER2-positive Breast Cancer
Cancer Trials Ireland
Phase 2
11
Galway, Dublin, Cork, Limerick
2023-10-26
Active, closed
BioDulse II: The Effect of an Irish Seaweed Protein Extract on Glucose Control in Adults With Type 2 Diabetes
NCT05986253 Type 2 Diabetes
University of Limerick
Not applicable
10
Limerick
2023-08-07
Active, closed
PROPEL-2: Prophylactic Negative Pressure Wound Therapy in Laparotomy Wounds
NCT05977816 Wound Surgical, Wound Infection, Cosmesis
Royal College of Surgeons, Ireland
Not applicable
2,000
Castlebar, Dublin, Galway, Letterkenny, Limerick, Sligo, Waterford
2023-07-14
Recruiting
Early Detection & Intervention of Cerebral Palsy in Ireland
NCT05907837 Cerebral Palsy, Neurodevelopmental Disorders
University College Cork
Observational
1,500
Cork, Dublin, Limerick
2023-07-01
Active, closed
Adagrasib in Patients With KRASG12C-mutant NSCLC Who Are Elderly or Have Poor Performance Status
NCT05673187 NSCLC Stage IV, KRAS P.G12C
ETOP IBCSG Partners Foundation
Phase 2
68
Dublin, Limerick, Waterford
2023-06-12
Recruiting
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
NCT05633654 Triple Negative Breast Cancer
Gilead Sciences
Phase 3
1,514
Dublin, Limerick, Wilton
2022-12-12
Active, closed
A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy
NCT05444257 Cystic Fibrosis
Vertex Pharmaceuticals Incorporated
Phase 3
822
Cork, Dublin, Limerick
2022-11-08
Recruiting
A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)
NCT05519085 Relapsed or Refractory Multiple Myeloma
Celgene
Phase 3
810
Galway, Cork, Dublin, Limerick
2022-09-20
Active, closed
A Phase III Study of Ceralasertib Plus Durvalumab Versus Docetaxel in Patients With Non Small Cell Lung Cancer (NSCLC) Whose Disease Progressed On or After Prior Anti PD (L)1 Therapy And Platinum Based Chemotherapy
NCT05450692 Advanced or Metastatic Non-Small Cell Lung Cancer
AstraZeneca
Phase 3
594
Cork, Dublin, Limerick
2022-09-15
Recruiting
A Trial of 5 Fraction Prostate SBRT Versus 5 Fraction Prostate and Pelvic Nodal SBRT
NCT05613023 Prostate Cancer
Institute of Cancer Research, United Kingdom
Phase 3
1,128
Cork, Dublin, Limerick
2022-09-09
Recruiting
Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation
NCT05243797 Multiple Myeloma
European Myeloma Network B.V.
Phase 3
1,594
Cork, Dublin, Galway, Limerick
2022-09-08
Recruiting
ADT +/- Darolutamide in de Novo Metastatic Prostate Cancer Patients With Vulnerable Functional Ability (PEACE6-Vulnerable)
NCT04916613 Prostate Cancer Metastatic
UNICANCER
Phase 3
300
Dublin, Limerick
2022-04-19
Active, closed
A Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician's Choice of Adjuvant Endocrine Monotherapy in Participants With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer (lidERA Breast Cancer)
NCT04961996 Early Breast Cancer
Hoffmann-La Roche
Phase 3
4,170
Cork, Dublin, Galway, Limerick, Waterford
2021-08-27
Active, closed
Tafasitamab + Lenalidomide + R-CHOP Versus R-CHOP in Newly Diagnosed High-intermediate and High Risk DLBCL Patients
NCT04824092 Diffuse Large B-cell Lymphoma
Incyte Corporation
Phase 3
899
Dublin, Limerick
2021-05-11
Recruiting
Efficacy and Safety of Nemtabrutinib (MK-1026) in Participants With Hematologic Malignancies (MK-1026-003)
NCT04728893 Hematologic Malignancies, Waldenstroms Macroglobulinaemia, Non-Hodgkins Lymphoma, Chronic Lymphocytic Leukaemia
Merck Sharp & Dohme LLC
Phase 2
490
Dublin, Limerick
2021-04-05
Active, closed
Ibrutinib Monotherapy Versus Fixed-duration Venetoclax Plus Obinutuzumab Versus Fixed-duration Ibrutinib Plus Venetoclax in Patients With Previously Untreated Chronic Lymphocytic Leukaemia (CLL)
NCT04608318 Chronic Lymphoid Leukemia
German CLL Study Group
Phase 3
897
Cork, Dublin, Galway, Limerick, Waterford
2021-03-01
Active, closed
Phase 3 Study of MRTX849 (Adagrasib) vs Docetaxel in Patients With Advanced Non-Small Cell Lung Cancer With KRAS G12C Mutation
NCT04685135 Metastatic Non Small Cell Lung Cancer, Advanced Non Small Cell Lung Cancer
Mirati Therapeutics Inc.
Phase 3
453
Tallaght, Dublin, Galway, Limerick
2021-02-23
Active, closed
A Study of Trastuzumab Deruxtecan (T-DXd) Versus Trastuzumab Emtansine (T-DM1) in High-risk HER2-positive Participants With Residual Invasive Breast Cancer Following Neoadjuvant Therapy (DESTINY-Breast05)
NCT04622319 HER2-Positive Primary Breast Cancer, Residual Invasive Breast Cancer
Daiichi Sankyo
Phase 3
1,600
Dublin, Cork, Limerick
2020-12-04
Recruiting
Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7
NCT04613596 Advanced Non-Small Cell Lung Cancer, Metastatic Non-Small Cell Lung Cancer
Mirati Therapeutics Inc.
Phase 2/3
626
Cork, Dublin, Galway, Limerick, Waterford
2020-12-02
Active, closed
Sacituzumab Govitecan in Primary HER2-negative Breast Cancer
NCT04595565 HER2-negative Breast Cancer, Triple Negative Breast Cancer
GBG Forschungs GmbH
Phase 3
1,332
Cork, Dublin, Limerick, Waterford
2020-10-28
Active, closed
Real World Clinical Outcomes With Novel Modulator Therapy Combinations in People With CF (RECOVER)
NCT04602468 Cystic Fibrosis, Cystic Fibrosis Liver Disease, Cystic Fibrosis in Children, Adherence, Medication
Royal College of Surgeons, Ireland
Phase 4
206
Dublin, Limerick, Tallaght
2020-09-03
Active, closed
A Study of Gilteritinib Versus Midostaurin in Combination With Induction and Consolidation Therapy Followed by One-year Maintenance in Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndromes With Excess Blasts-2 With FLT3 Mutations Eligible for Intensive Chemotherapy
NCT04027309 Acute Myeloid Leukemia, Myelodysplastic Syndrome With Excess Blasts-2
Stichting Hemato-Oncologie voor Volwassenen Nederland
Phase 3
777
Cork, Dublin, Galway, Limerick
2019-12-20
Active, closed
A Study to Investigate the Efficacy of Zanubrutinib Plus Rituximab Compared With Bendamustine Plus Rituximab in Adults With Previously Untreated Mantle Cell Lymphoma Who Are Ineligible for Stem Cell Transplantation
NCT04002297 Mantle Cell Lymphoma; Non-Hodgkin Lymphoma
BeOne Medicines
Phase 3
510
Cork, Dublin, Galway, Limerick, Waterford
2019-08-20
Recruiting
Pan Tumor Rollover Study
NCT03899155 Cancer
Bristol-Myers Squibb
Phase 2
1,500
Dublin, Limerick
2019-08-09
Active, closed
A Study of Nivolumab, Nivolumab Plus Ipilimumab, or Investigator's Choice Chemotherapy for the Treatment of Participants With Deficient Mismatch Repair (dMMR)/Microsatellite Instability High (MSI-H) Metastatic Colorectal Cancer (mCRC)
NCT04008030 Metastatic Colorectal Cancer
Bristol-Myers Squibb
Phase 3
839
Dublin, Limerick
2019-08-05
Recruiting
The Mechanical Characterisation of Human Saphenous and Popliteal Vein
NCT04016649 Peripheral Vascular Diseases
University Hospital of Limerick
Observational
50
Limerick
2019-01-21
Active, closed
Feasibility Study of the Pilot Post-primary Active School Flag (PPASF) Program
NCT03847831 Physical Activity, Health Behavior, Health Knowledge, Attitudes, Practice, Educational Problems
University of Limerick
Not applicable
9,000
Limerick
2018-09-01
Active, closed
A Study in Ovarian Cancer Patients Evaluating Rucaparib and Nivolumab as Maintenance Treatment Following Response to Front-Line Platinum-Based Chemotherapy
NCT03522246 Epithelial Ovarian Cancer, Primary Peritoneal, Fallopian Tube Cancer, Newly Diagnosed
pharmaand GmbH
Phase 3
1,097
Cork, Limerick, Waterford
2018-05-14
Active, closed
Efficacy and Safety of Pembrolizumab (MK-3475) With Platinum Doublet Chemotherapy as Neoadjuvant/Adjuvant Therapy for Participants With Resectable Stage II, IIIA, and Resectable IIIB (T3-4N2) Non-small Cell Lung Cancer (MK-3475-671/KEYNOTE-671)
NCT03425643 Non-small Cell Lung Cancer
Merck Sharp & Dohme LLC
Phase 3
797
Wilton, Dublin, Limerick
2018-04-24
Recruiting
The Biomechanical Study of Diseased Human Carotid, Femoral and Abdominal Aortic Tissue
NCT05802706 Vascular Diseases
University Hospital of Limerick
Observational
300
Limerick
2016-01-01
Active, closed
Add-Aspirin: A Trial Assessing the Effects of Aspirin on Disease Recurrence and Survival After Primary Therapy in Common Non Metastatic Solid Tumours
NCT02804815 Cancer, Breast Cancer, Prostate Cancer, Colorectal Cancer
University College, London
Phase 3
11,000
Cork, Dublin, Galway, Limerick, Sligo, Waterford
2015-10
Active, closed
PALbociclib CoLlaborative Adjuvant Study
NCT02513394 Breast Cancer
Alliance Foundation Trials, LLC.
Phase 3
5,796
Cork, Dublin, Limerick, Sligo, Waterford
2015-08
Active, closed
Pregnancy Outcome and Safety of Interrupting Therapy for Women With Endocrine Responsive Breast Cancer
NCT02308085 Early Breast Cancer
ETOP IBCSG Partners Foundation
Not applicable
518
Dublin, Galway, Limerick, Waterford
2014-12-04
Active, closed
TAILORx Tissue Bank
NCT02050750 Breast Cancer
Cancer Trials Ireland
Observational
600
Cork, Donegal, Dublin, Galway, Limerick, Sligo, Waterford
2013-12
Recruiting
Breast Cancer Proteomics and Molecular Heterogeneity
NCT01840293 Primary Breast Cancer, Recurrent/Metastatic Breast Cancer
Cancer Trials Ireland
Observational
1,780
Cork, Dublin, Limerick, Waterford
2013-02
Active, closed
Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer
NCT01272037 Breast Ductal Carcinoma In Situ, Invasive Breast Carcinoma, Multicentric Breast Carcinoma, Multifocal Breast Carcinoma
National Cancer Institute (NCI)
Phase 3
5,018
Cork, Dublin, Mount Merrion, Galway, Limerick, Sligo, Waterford, Letterkenny
2011-02-28
Active, closed
Hormone Therapy With or Without Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Negative Breast Cancer (The TAILORx Trial)
NCT00310180 Breast Adenocarcinoma, Hormone Receptor Positive, Stage IA Breast Cancer AJCC v7, Stage IB Breast Cancer AJCC v7
National Cancer Institute (NCI)
Phase 3
10,273
Cork, Dublin, Mount Merrion, Galway, Limerick, Sligo, Waterford, Letterkenny
2006-04-07
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Priya Life Science (2026). Clinical trial register: studies with an Irish investigative site, filtered. Derived from ClinicalTrials.gov, U.S. National Library of Medicine. Retrieved 22 September 2026. https://priyalifescience.com/clinical-trials-ireland/city/limerick

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Listing here is informational and not medical advice; eligibility is determined by each study team. Patients should discuss participation with their clinician. For trials across the wider EU, see the EU Clinical Trials Tracker.