Food-related Quality of Life in Patients With Cancer

NCT07437326 · tracked via the Priya Life Science France tracker

Sponsor

Hospices Civils de Lyon

Phase

Observational

Started

2026-03

Last updated

2026-02-27

Condition(s) studied

Breast CancerHead and Neck CancersGynecologic CancerGastrointestinal CancerLung Cancer

Investigational drug(s) / intervention(s)

Self-reported questionnairesSalivary and sensory tests

Self-reported questionnaires: Self-reported questionnaires will be used to asses patient's food-related quality of life (QVA questionnaire), global quality of life (EORTC QLQ-C30 questionnaire), evaluation of oral symptoms and perceptions.

Salivary and sensory tests: Objective tests will be performed to measure the salivary quality and quantity and taste and smell perceptions.

Study summary

Food plays a fundamental role in quality of life. In patients with cancer psychological burden and treatment-related side effects can impact appetite, taste perception and pleasure of eating, making nutritional management more challenging.

Given the central role of food and nutrition in maintaining physical health and psychological well-being, it is essential to better understand the factors that contribute to food-related quality of life in order to improve the quality of life of patients with cancer. Despite the importance of these psychological aspects, current assessments tools do not adequately measure the impact of cancer on the food-related quality of life.

In a study entitled "CANUT-QVA" a specific questionnaire measuring nine dimensions of food related quality of life was developed, allowing for a better understanding of how patients perceive and experience their diet. This instrument consists of 46 items and explores nine dimensions, its use showing a significant decrease in food related quality of life of patients with breast cancer, opening the way for targeted interventions to improve nutritional well being and overall quality of life in cancer patients.

The present study aims to analyse various factors - such as oral health, sensory profile and clinical characteristics - associated with food-related quality of life in patients with cancer (gastrointestinal, head and neck, lung, breast and gynecologic cancer) during or after treatment, in order to develop a predictive model of food related quality of life. The main objective of this project is to identify the population at highest risk, so as to better tailor nutritional interventions for patients with cancer, considering both the type of treatment received and the phase, during or after treatment. The food-related quality of life questionnaire containing 46 items will be used to measure the primary outcome.

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Inclusion Criteria: * Patient aged 18 years or older; * Patient with gastrointestinal, breast, gynecologic, head and neck, lung * Patient receiving a cancer treatment (chemotherapy, targeted therapy, immunotherapy, etc.) from at least two months; * Patients having undergone anticancer treatment (chemotherapy, targeted therapy, immunotherapy, etc.) having completed it at least 3 months and no more than 12 months before inclusion; * Patient capable of filling a questionnaire; * Patient having given his free, informed and express consent. Exclusion Criteria: * \- Patient having a radiotherapy treatment for a head or neck cancer; * Patient having presented nausea and vomiting during the last 24 hours; * Patient with severe inflammation of the mouth or throat (ulcers, mucus); * Patient with cognitive disorders and memory loss; * Pregnant women or breastfeeding; * Adult under legal protection (guardianship, curatorship).

Primary outcome measure(s)

The food-related quality of life in patients with cancer (gastrointestinal, breast, head and neck, gynecologic, lung). — day of inclusion
The food-related quality of life questionnaire containing 46 items will be used to measure the outcome. The questionnaire uses a Likert scale: 1 = never; 2 = sometimes; 3 = often; 4 = always.

Trial sites (3)

Facility	City	Region
Hôpital Femme Mère Enfant	Bron	France
Hôpital de la Croix Rousse	Lyon	France
Hôpital Lyon Sud	Oullins	France

More Hospices Civils de Lyon trials in France

MEG Versus EEG HR for the Localization of the Epileptogenic Zone as Part of the Pre-surgical Assessment of Epilepsy Recruiting

Trial of FOLFIRI + Zimberelimab + Domvanalimab vs FOLFIRI With a Hybrid Synthetic Control Arm in Second Line Treatment of Neuroendocrine Carcinoma of Gastro-enteropancreatic or Unknown Origin (REWENEC 01) Starting soon

EARLY Intervention in Parent-professional Cooperation in Cerebral Palsy Recruiting

Evaluation of Penile Prosthesis Pump Manipulation Recruiting

Viscoelastic Tests (VET) Versus Conventional Coagulation Tests (CCT) for Management of Trauma-Induced Coagulopathy Starting soon

Other trials for the same condition

Assessment of Adherence to Remotely Monitored Physical Activity Tracked on a Smartwatch, and Its Impact on Reducing Fatigue 3 Months After Adjuvant Chemotherapy for Cancer Recruiting

Biomedical Innovation for Facial Bone Reconstruction in Oncology: BIOFACE PASS a Medico-economic Study Describing the Standard Pathway of Patients Treated by Free Bone Flap Recruiting

In-depth Characterization of Circulating and Infiltrating Immune Subsets and Tumor Cells in Cancer Patients Starting soon

A Study of Dato-DXd Versus Investigator's Choice Chemotherapy in Patients With Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer, Who Are Not Candidates for PD-1/PD-L1 Inhibitor Therapy (TROPION-Breast02) Active, not recruiting

A Clinico-biological Database of Lung Cancers Recruiting

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07437326 on ClinicalTrials.gov ↗ ← All trials in France