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Clinical Trials in France / NCT05156385
Recruiting Not applicable

Sexual Dysfunction in Hypertensive Women

NCT05156385 · tracked via the Priya Life Science France tracker
Phase
Not applicable
Started
2022-06-27
Last updated
2026-06-01

Condition(s) studied

Hypertension

Investigational drug(s) / intervention(s)

Blood sample for the determination of antihypertensives or their metabolites.Questionnaire on sexual activityScale on hospital anxiety and depressionMorisky Questionaire

Blood sample for the determination of antihypertensives or their metabolites.: 15 ml of Blood sample for the determination of antihypertensives or their metabolites

Questionnaire on sexual activity: Questionnaire on sexual activity in women

Scale on hospital anxiety and depression: Scale on hospital anxiety and depression to detect anxious and depressive symptoms (14 questions)

Morisky Questionaire: anti-hypertensive medication compliance questionnaire

Study summary

Several studies describe the existence of an association between sexual dysfunction and high blood pressure (hypertension), most often characterized by a decrease in the number of orgasms and the existence of dyspareunia.

Hypertension is a contributing factor, and nonadherence to medication could amplify it.

There are several ways to assess adherence to treatment: the use of declarative questionnaires, a method not without criticism because it is subject to the subjectivity of the declaration by the patient; and drug dosages, a standard technique, although insufficiently disseminated due to the high cost and greater weight of the survey protocols. Drug non-compliance is multifactorial. In addition, it has been shown that having undesirable drug effects and / or being afraid of developing them is one of the major causes of non-compliance with antihypertensive treatments.

The investigators hypothesize that DS is significantly more common among hypertensive women treated with non-observers compared to hypertensive women treated with observers.

The main objective is to compare the prevalence of sexual dysfunction between a group of hypertensive women treated as observers and a group of hypertensive women treated as non-observers.

Eligibility

Sex
FEMALE
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Women over 18, * Hospitalized or received in consultation for the management of hypertension treated in one of the hypertension and therapeutic, nephrology or cardiology departments participating in the study, with confirmed hypertension, treated with the following dosable antihypertensive agent(s): diltiazem, verapamil, acebutolol, atenolol, nébivolol, bisoprolol, metoprolol, propranolol, amiloride, furosemide, hydrochlorothiazide, indapamide, spironolactone, spironolactone, Lorsartan, Irbesartan, Ramipril, Perindopril, Amlodipine, * Having signed the informed consent form. * Beneficiary or affiliated to a French Social insurance Exclusion Criteria: * Patients with bariatric surgery, * Patients under guardianship/trusteeship/protection of justice, * Patients with diagnosed and treated psychosis or depression, - Pregnant or nursing women.

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
LAZARO Delphine Toulouse CHU de Toulouse Recruiting

More University Hospital, Toulouse trials in France

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05156385 on ClinicalTrials.gov ↗ ← All trials in France