peroxide -based in office tooth bleachingnon-peroxide -based in office tooth bleaching
peroxide -based in office tooth bleaching: Participants will receive an in-office peroxide-based tooth bleaching treatment using the bleaching system according to the manufacturer's instructions.
non-peroxide -based in office tooth bleaching: Participants will receive an in-office non- peroxide-based tooth bleaching treatment using the bleaching system according to the manufacturer's instructions.
Study summary
This randomized clinical trial aims to compare the effectiveness of peroxide and non-peroxide in-office tooth bleaching systems. The study will evaluate tooth whitening efficacy, color durability over time, and tooth sensitivity after treatment. Participants will receive one of the two bleaching treatments and will be followed for six months to assess the clinical outcomes and compare the performance of both systems.
Eligibility
Sex
ALL
Min age
18 Years
Max age
45 Years
Healthy volunteers
Accepted
Inclusion Criteria:
* Adults aged 18-45 years.
* Good general health.
* Presence of all maxillary anterior teeth free from restorations, caries, or structural defects.
* Baseline tooth shade suitable for bleaching assessment.
* Good oral hygiene and periodontal health.
* Willingness to comply with the study protocol and attend all follow-up visits.
* Signed informed consent.
Exclusion Criteria:
* Pregnancy or lactation.
* History of tooth hypersensitivity.
* Active caries or defective restorations in the anterior teeth.
* Intrinsic tooth discoloration (e.g., fluorosis, tetracycline staining).
* Ongoing orthodontic treatment.
* Smoking.
* Use of tooth-whitening products within the previous 6 months.
* Allergy to any component of the bleaching materials.
Primary outcome measure(s)
Bleaching efficacy measured by Whiteness Index for Dentistry (WID) — Baseline, immediately after treatment, 1 month, 3 months, and 6 months after treatment Bleaching efficacy will be assessed using the Whiteness Index for Dentistry (WID) obtained by spectrophotometric measurements of the anterior teeth.
Color durability measured by CIEDE2000 color difference (ΔE00) — Baseline, immediately after treatment, 1 month, 3 months, and 6 months after treatment Color durability will be evaluated using spectrophotometric color measurements and expressed as CIEDE2000 color difference (ΔE00).
Tooth sensitivity assessed using the Visual Analog Scale (VAS) — Daily during the 14-day treatment period ooth sensitivity will be evaluated using a 0-10 Visual Analog Scale (VAS), where 0 indicates no pain and 10 indicates the worst possible pain
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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