Effect of Thymoquinone 0.2% Gel on Bone Density, Bone Width, and Socket Preservation After Tooth Extraction

NCT07765745 · tracked via the Priya Life Science Egypt tracker

Sponsor

Kafrelsheikh University

Phase

Not applicable

Started

2026-02-01

Last updated

2026-08-14

Condition(s) studied

Radiographic EvaluationBone DensityBone WidthSocket PreservationTooth ExtractionThymoquinone

Investigational drug(s) / intervention(s)

Gel foamThymoquinone gel + gel foamNano-formulated 0.2% thymoquinone gel + gel foam

Gel foam: Patients will receive gel foam only.

Thymoquinone gel + gel foam: Patients will receive 0.2% thymoquinone gel + gel foam.

Nano-formulated 0.2% thymoquinone gel + gel foam: Patients will receive nano-formulated 0.2% thymoquinone gel + gel foam.

Study summary

This study aims to evaluate the clinical and radiographic effects of 0.2% Thymoquinone gel on bone density, bone width, and socket preservation after tooth extraction.

Eligibility

Sex

ALL

Min age

18 Years

Max age

50 Years

Healthy volunteers

Inclusion Criteria: * Age: 18-50 years. * Both sexes. * Patients requiring extraction of upper posterior teeth will be recruited. Exclusion Criteria: * Healthy subjects with intact sockets after extraction. * Normal mouth opening and good oral hygiene. * No systemic conditions affecting bone healing.

Primary outcome measure(s)

Change in alveolar bone density after tooth extraction — 3 months after tooth extraction
Alveolar bone density will be assessed radiographically using cone-beam computed tomography (CBCT). The change in bone density from baseline to the specified postoperative assessment will be compared.

Trial sites (1)

Facility	City	Region	Status
Kafrelsheikh University	Kafr ash Shaykh	Kafrelsheikh	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07765745 on ClinicalTrials.gov ↗ ← All trials in Egypt