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Clinical Trials in Egypt / NCT07445607
Starting soon Not applicable

"Mulligan Technique vs Phonophoresis With Chitosan for Patellofemoral Pain"

NCT07445607 · tracked via the Priya Life Science Egypt tracker
Phase
Not applicable
Started
2026-02-15
Last updated
2026-03-03

Condition(s) studied

Patellofemoral Pain Syndrome

Investigational drug(s) / intervention(s)

Mulligan techniquePhonophoresis with Chitosan GelStandard Physical Therapy Exercise Program

Mulligan technique: Each mobilization with movement (MWM) is performed in three sets of 10 repetitions, with a 30-second rest interval between sets, 3 times per week for 6 weeks, before hip and knee strengthening exercises.

Phonophoresis with Chitosan Gel: Phonophoresis (ultrasound with chitosan gel) is applied at 1 MHz, 1.0 W/cm², continuous mode, for 5 minutes, 3 times per week for 6 weeks before hip and knee exercises.

Standard Physical Therapy Exercise Program: Participants attend 3 sessions per week for 6 weeks. Each session includes stretching and hip and knee focused exercises. Progression involves weekly increases in repetitions and resistance based on pain levels (less than 3/10).

Study summary

Patellofemoral pain syndrome (PFPS) is a common knee condition causing pain and dysfunction. This study aims to compare the effectiveness of two physical therapy treatments for PFPS: Mulligan mobilization with movement technique versus phonophoresis with chitosan gel.

Forty-five participants with patellofemoral pain syndrome will be randomly assigned to one of three groups: (1) Mulligan technique group, (2) Phonophoresis with chitosan gel group, or (3) Control group receiving standard physical therapy exercises. Each group will receive treatment 3 times per week for 4 weeks.

The researchers want to determine which treatment is more effective in improving neuromuscular control, reducing pain, and improving function in patients with patellofemoral pain syndrome. Participants will be assessed before and after the treatment period.

This study may help physical therapists and healthcare providers choose the most effective treatment approach for patients with patellofemoral pain.

Eligibility

Sex
ALL
Min age
18 Years
Max age
35 Years
Healthy volunteers
No
Inclusion Criteria: * Insidious onset of anterior knee pain * Retro patellar or peripatellar pain * Pain duration more than four weeks (chronic/subacute) * Pain severity ≥ 3/10 on Visual Analog Scale (VAS) * Pain during at least two of the following activities: stair ascent or descent, squatting, prolonged sitting (theater sign), or kneeling * Positive patellar compression test (pain reproduced by compressing the patella into the trochlear groove) * Patellar tenderness along the medial or lateral borders * Age between 18 and 35 years * Baseline Kujala score (Arabic version): approximately 67-71 (indicating moderate to severe dysfunction) Exclusion Criteria: * Traumatic injury (e.g., dislocation, fracture, ligament or meniscus pathology) * Inflammatory arthritis (e.g., rheumatoid arthritis, gout) * Prior knee surgery * Current use of NSAIDs or corticosteroids

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Ahram Canadian unveracity Cairo Giza Governorate

More Ahram Canadian University trials in Egypt

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07445607 on ClinicalTrials.gov ↗ ← All trials in Egypt