Analgesia Nociception Index Monitoring in Trigeminal Cardiac Reflex During Nasal Septoplasty

NCT07435870 · tracked via the Priya Life Science Egypt tracker

Sponsor

Fayoum University Hospital

Phase

Observational

Started

2026-04-01

Last updated

2026-09-10

Condition(s) studied

ENT Disease

Study summary

This study aims to evaluate the utility of Analgesia Nociception Index (ANI) monitoring as a predictive and preventive tool for TCR during septoplasty. By comparing standard anesthetic monitoring with ANI-guided analgesia, this research seeks to determine whether maintaining optimal autonomic balance can reduce the incidence of trigeminal cardiac reflex (TCR) and improve intraoperative cardiovascular stability.

Eligibility

Sex

ALL

Min age

18 Years

Max age

60 Years

Healthy volunteers

Inclusion Criteria: * Age 18-60 years. * American society of anesthesiologist physical status I-II * Indicated for primary septoplasty. Exclusion Criteria: * Known cardiac arrhythmias or conduction disorders. * Use of beta-blockers or antiarrhythmic medications. * Previous nasal surgery and Combined nasal procedures. * Inability to obtain reliable Analgesia Nociception Index readings.

Primary outcome measure(s)

Primary Outcome - Incidence of trigeminal cardiac reflex — 3 hours
Defined as a decrease in heart rate \>20% from baseline during surgery.

Trial sites (1)

Facility	City	Region	Status
Fayoum univeristy hospital	Al Fayyum	Faiyum Governorate

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07435870 on ClinicalTrials.gov ↗ ← All trials in Egypt