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Clinical Trials in Egypt / NCT07340242
Recruiting Not applicable

Dentoskeletal Effects of 3D-Printed Fixed Twin Block Versus MARA Appliances in Management of Skeletal Class II

NCT07340242 · tracked via the Priya Life Science Egypt tracker
Phase
Not applicable
Started
2025-04-27
Last updated
2026-01-14

Condition(s) studied

Class II MalocclusionMandibular Deficiency

Investigational drug(s) / intervention(s)

MARA appliancefixed twin block

MARA appliance: CAD/CAM 3D printed mandibular anterior repositioning appliance

fixed twin block: CAD/CAM 3D printed fixed twin block

Study summary

Objective: to evaluate the dentoskeletal effects of CAD/CAM 3D-Printed fixed twin block versus MARA appliances in the management of skeletal class II due to Mandibular Deficiency in Preadolescence Class II malocclusion is considered one of the most commonly observed problems among orthodontic patients, representing around one-third of the patients seeking orthodontic treatment reflecting a significant economic impact. Various removable and fixed functional appliances are commonly used to stimulate mandibular growth. Fixed Twin-block appliance has advantages compared with removable Twin-block and Herbst appliances. The mandibular anterior repositioning appliance is referred to as M.A.R.A. appliance.

Materials and method: The study design is a randomized controlled trial in which the control group and intervention groups will be assessed as parallel groups with a 1:1:1 allocation ratio. Sixty subjects will be enrolled in this research. They will be divided equally into three groups: untreated control, MARA group and Twin block group

Eligibility

Sex
ALL
Min age
9 Years
Max age
14 Years
Healthy volunteers
No
Inclusion Criteria: 1. Skeletal Class II malocclusion due to mandibular retrusion. 2. Overjet ≥ 6.0 mm. 3. Normal or low-angle growth pattern. 4. Minimum crowding in the mandibular arch. 5. Undergoing circumpubertal phase of skeletal development (CVMI 2, 3, and 4) Exclusion Criteria: 1. Clinical signs and symptoms of temporomandibular disorder. 2. Systemic disease affecting bone and general growth. 3. Previous orthodontic treatment 4. Cleft lip or palate. 5. Congenital craniofacial deformity. 6. Abnormal oral habits.

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Faculty of dentistry, Mansoura university Al Mansurah Dakahlia Governorate Recruiting

More Mansoura University trials in Egypt

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07340242 on ClinicalTrials.gov ↗ ← All trials in Egypt