Searching electrical activity registered by EEG in acute ischemic and hemorrhagic stroke and comparing these parameters to the poststroke recovery patterns to investigate the role of EEG as a differentiation tool and as a predictor of post-stroke recovery.
Eligibility
Sex
ALL
Min age
18 Years
Max age
80 Years
Healthy volunteers
No
Inclusion Criteria:
* Age above 18 and below 80 years.
* Acute Ischemic stroke: ischemic arteria cerebri media infarct confirmed by MRI.
* Acute Hemorrhagic stroke: spontaneous intraparenchymal bleeding confirmed by CT.
* Stroke onset \<72 hours before expected time of performing EEG.
* First-ever ischemic stroke.
* Measurable deficit on the National Institute of Health Stroke Scale (NIHSS).
* Able to give and sign informed consent.
Exclusion Criteria:
* Transient Ischemic Attacks (TIAs).
* Greater than 72 hours past the initial insult.
* Patients with subarachnoid haemorrhage, traumatic haemorrhage (epidural/subdural bleeding), cerebral venous sinus thrombosis, indication for urgent neurosurgical intervention.
* History of other central nervous system diseases.
* Any signs unfit for MRI/EEG scan.
* Injury or active infection of electrode cap placement area.
* Claustrophobia; recognition disorder.
* Known skull defect or head trauma.
* Previous neurological procedure (metallic implant, brain pace, cranial operation history).
* Significant physical impairment that would restrict the ability to use the portable EEG devices.
* Presence of malignancy or systemic rheumatic disease
* Non-stroke disease or lesion affecting the sensorimotor system.
* Alcohol or drug addiction.
* Presence of pump/shunt.
* Presence of Malignancy.
* Presence of severe cognitive impairment.
* History of epilepsy or taking medication due to epilepsy.
Primary outcome measure(s)
Proportion of Participants With Focal Slowing in the Stroke-Affected Hemisphere — Baseline (within 72 hours of stroke onset) Presence of focal slowing (e.g., increased delta or theta activity) in the stroke-affected hemisphere versus the unaffected hemisphere. Patterns categorized as "ischemic" or "hemorrhagic."; this will be measured in percentage (%).
Proportion of Participants With Interhemispheric Asymmetry in EEG Waveforms — Baseline (within 72 hours of stroke onset) Qualitative assessment of EEG asymmetry between affected and unaffected hemispheres at baseline. Frequency of each will be measured in percentage (%).
Proportion of Participants With Absent or Diminished EEG Reactivity — Baseline (within 72 hours of stroke onset) Absence or reduction in EEG reactivity to external stimuli (e.g., auditory, tactile) in the affected hemisphere; this will be measures by precentage (%).
Proportion of Participants With Epileptiform Activity on EEG — Baseline (within 72 hours of stroke onset) Presence of epileptiform discharges (e.g., spikes or sharp waves) on EEG in the stroke-affected hemisphere; thsi will be measured by precentage (%).
Trial sites (1)
Facility
City
Region
Status
Neurology Department, Faculty of Medicine, Assiut University
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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