New Method to Close Nasal Septal Perforation

Condition(s) studied

Investigational drug(s) / intervention(s)

Polycaprolactone nasal mesh: a 3-dimensional fabricated Polycaprolactone nasal mesh

Study summary

The goal of this clinical trial is to investigate if a 3-dimensional fabricated nasal mesh works to close nasal septal perforations. Under general anesthesia, during nasal septal perforation repair surgery, the investigator will place the mesh between the elevated mucoperichondrial flaps opposite the site of the perforation and confirm its original position at both sides under nasal endoscope. Endoscopic examination for septal mucosa status will be done monthly for a three months follow up period.

Eligibility

Primary outcome measure(s)

• Mean Change in Post-operative healing of septal perforation — for a three months follow up period
  Endoscopic evaluation of nasal septal mucosa status will be classified as complete bilateral healing, complete unilateral healing, no healing, and perforation.

Trial sites (1)

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