The Effect of Resistance Exercise in Patients With Lower Limb Lymphedema (the LymphEx Study)

Condition(s) studied

Investigational drug(s) / intervention(s)

Resistance exercise: Supervised resistance exercise targeted at the larger muscle groups in the lower limbs, 5 exercises, 3 sets of 10RM

Study summary

The aim of the study is to investigate the short-term (within 2 weeks) effects of resistance exercise with and without compression garments on lower limb lymphedema(LLL). Additionally, the study will explore the immediate response in LLL to resistance exercise (2 hours and 24 hours post-exercise).

Participants will continously wear a circumfencential sensor at the calf (CIMON from Icompression) under a compression garment and an activity tracker (SENS Motion from SENS Innovation Aps) at the thigh for 3 periods (two with supervised exercise sessions of 2 weeks and one control period).

Participants will attend supervised resistance exercise 2-3 times per week for 2 periods of 2 weeks (one with compression garment and one without). Assessments with the principal investigator will be scheduled before and after every 2 week period. Participants will keep a digital diary or diary in paper of their lymphedema related symptoms and experienced issues with the sensors or app.

Eligibility

Primary outcome measure(s)

• Lower leg circumference — 14 days
  circumferential sensor CIMON, measured in Picoferens (pF)

Trial sites (1)

Other trials for the same condition