NICardipine for Fast Achievement of Systolic BP Targets in ICH

NCT07044232 · tracked via the Priya Life Science Denmark tracker

Sponsor

Aarhus University Hospital

Phase

Phase 4

Started

2025-10-01

Last updated

2026-06-24

Condition(s) studied

Intracerebral Haemorrhage

Investigational drug(s) / intervention(s)

NicardipineGlyceryl trinitrate

Nicardipine: Nicardipine infusion based acute blood pressure lowering treatment

Glyceryl trinitrate: Glyceryltrinitrate based acute blood pressure lowering treatment

Study summary

Quality improvement study with a quasi-randomized design. The study monitors the effect of a gradually implemented treatment algorithm prioritizing intravenous antihypertensives (e.g., nicardipine) over long-acting nitrate patches. It aims to increase the proportion of patients reaching target systolic BP \<140 mmHg within 1 hour of hospital admission while monitoring safety, clinical outcomes, and healthcare resource utilization.

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Inclusion Criteria: * Age ≥18 years * Acute spontaneous Intracerberal Hemorrhage confirmed by imaging * Symptom onset to stroke center admission \<6 hours * Elevated systolic blood pressure (\>140 mmHg) at admission Exclusion Criteria: * Secondary causes of ICH (e.g., trauma, vascular malformation) * Presumed fatal bleeding at admission * Short remaining life expectancy (\<12 month)

Primary outcome measure(s)

Target blood pressure < 140 mmHg 1 hour after admission. — 1 hour after stroke center admission
Proportion of patients reaching systolic BP \<140 mmHg within 1 hour of stroke center admission

Trial sites (1)

Facility	City	Region	Status
Aarhus University Hospital	Aarhus	Denmark	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07044232 on ClinicalTrials.gov ↗ ← All trials in Denmark