Improving Dysregulated Neural Networks With EEG-neurofeedback

Condition(s) studied

Investigational drug(s) / intervention(s)

Neurofeedback: EEG-based neurofeedback, administered with the Neuroguide software.

Study summary

Comorbid PTSD in the context of chronic pain rehabilitation is a major problem. The lack of effective and efficient methods that can be integrated into current practice is needed. The current recommended treatments for PTSD leave room for supplementary approaches to achieve symptom reduction. PTSD is characterized by specific alterations of neural activity, and the DMN is known to be involved in this. Neurofeedback is the most current approach to altering neural activity patterns towards a norm pattern found in healthy subjects.

The aim of the present study is to assess whether EEG neurofeedback compared to an active control group receiving EEG sham neurofeedback is effective in alleviating PTSD symptoms and pain intensity in patients with chronic pain and comorbid PTSD after MVCs.

Eligibility

Primary outcome measure(s)

• Pain intensity rating — Before every nf-session and six months after the last session.
  Average pain intensity during the last day and current pain intensity before beginning the neurofeedback session, will be assessed on an 11-point numeric rating scale (NRS) ranging from 0 (no pain) to 10 (worst imaginable pain)
• EEG-power in alpha band — Before the first nf-session and after the last session (roughly six weeks later)
  37-channel EEG will be recorded, the alpha power seems to indicate cortical activity.

Trial sites (1)

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