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Clinical Trials in Denmark / NCT05731037
Active, not recruiting Not applicable

Influence of Restitution Time in Treatment of Patellar Tendinopathy

NCT05731037 · tracked via the Priya Life Science Denmark tracker
Phase
Not applicable
Started
2023-03-02
Last updated
2024-10-01

Condition(s) studied

Patellar TendinopathyJumper's Knee

Investigational drug(s) / intervention(s)

Resistance training for knee extensors

Resistance training for knee extensors: The exercise will be started at 60% of 1 repetition maximum (RM) and progressed to 75% of 1 RM during the first 3 weeks and maintained throughout the intervention period. The exercise will be performed slowly (6 s/ repetition).

Study summary

The purpose of the present project is to investigate if the restitution time from loading in an exercise-based 12 weeks rehabilitation regime for patellar tendinopathy influences the clinical outcome, tendon structure and function.

The investigators hypothesize that greater restitution from loading (1 exercise day per week) will yield a greater positive clinical outcome, and tissue structure and function in patients with patellar tendinopathy compared to less restitution (3 exercise days per week), when impact activities are restricted in both groups.

Eligibility

Sex
ALL
Min age
18 Years
Max age
60 Years
Healthy volunteers
No
Inclusion Criteria: * Sports active men and women. * Age (18-60) years old. * BMI (18.5-30) * Understand and read Danish * Uni- or bilateral patellar tendinopathy * Symptom onset \>90 days ago Exclusion Criteria: * Patellar tendinopathy longer than 24 months * Smoking * Previous surgery in the knee on the ipsilateral side. * Corticosteroid injection in the patellar tendon on the ipsilateral side within the last 6 months. * Any confounding diagnosis to the knee joint * Known arthritis * Known diabetes * Inability to follow rehabilitation or complete follow-ups * Enrolled in a resistance based-rehabilitation program for the affected patellar tendon within the previous three month * Have a work were it is not feasible to avoid pain provoking tasks Extra criteria sub-study one Inclusion criteria: • Five patients from the main study, rating "improved" and "not improved" respectively, will be invited to participate in sub-study one. Exclusion criteria: * Claustrophobia * Pregnancy * Breastfeeding Extra criteria sub-study two: Inclusion criteria: * Patients from the main study, that rate themselves 'not improved' in symptoms after 12 week. * Patients who have not achieved Patient Acceptable Symptom State (PASS) after week 20, 24, 28, 32, 36 and 40, will be invited to participate in sub- study two. Exclusion criteria: * Pregnancy * Breastfeeding * Previously had an allergic reaction for steroid (Depomedrol). * Previously had an allergic reaction for local anesthesia treatment.

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Department of Physical & Occupational Therapy/ Institute of Sports Medicine, Bispebjerg Hospital Copenhagen NV

More Bispebjerg Hospital trials in Denmark

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05731037 on ClinicalTrials.gov ↗ ← All trials in Denmark