D615L vs Zeiss 839MP: Visual Quality

NCT07571694 · tracked via the Priya Life Science China tracker

Sponsor

Shanghai 10th People's Hospital

Phase

Observational

Started

2025-04-01

Last updated

2026-05-06

Condition(s) studied

Cataract

Investigational drug(s) / intervention(s)

Trifocal IOL

Trifocal IOL: implanted D615L

Study summary

The goal of this prospective cohort study is to compare visual quality after cataract surgery in patients implanted with a new domestic trifocal intraocular lens (D615L) versus the Zeiss AT LISA tri 839MP. The main question it aims to answer is: Is the uncorrected distance, intermediate, and near visual acuity achieved with D615L non-inferior or superior to that achieved with the Zeiss 839MP? Participants diagnosed with age-related cataract will undergo phacoemulsification and receive one of the two intraocular lenses. They will attend follow-up visits where uncorrected visual acuity, defocus curves, and the VF-14 questionnaire will be assessed over a follow-up period of at least 6 months.

Eligibility

Sex

ALL

Min age

50 Years

Max age

—

Healthy volunteers

Inclusion Criteria: * diagnosed age-related cataract; * preoperative corneal astigmatism \<1.0 D; * endothelial cell count \>2000/mm²; * signed informed consent and ability to complete 6-month follow-up Exclusion Criteria: * prior corneal refractive, glaucoma or vitreoretinal surgery; * intraoperative posterior capsule rupture, zonular dehiscence or vitreous loss; * corneal pathology, macular edema or optic neuropathy affecting visual assessment; * active ocular inflammation, glaucoma, maculopathy or diabetic retinopathy; * uncontrolled systemic disease such as diabetes or autoimmune disorders.

Primary outcome measure(s)

UIVA — From enrollment to the end of treatment at 6 months
uncorrected-intermediate visual acuity

Trial sites (1)

Facility	City	Region	Status
Shanghai Tenth People's Hospital	Shanghai	Shanghai Municipality

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07571694 on ClinicalTrials.gov ↗ ← All trials in China