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Clinical Trials in China / NCT07453992
Recruiting Not applicable

Postoperative Rotational Dynamics of Three Toric Intraocular Lens Designs

NCT07453992 · tracked via the Priya Life Science China tracker
Sponsor
Jin Yang
Phase
Not applicable
Started
2025-01-01
Last updated
2026-03-06

Condition(s) studied

Cataract

Investigational drug(s) / intervention(s)

TECNIS Toric II (ZCU)AcrySof IQ ToricAT TORBI 709M

TECNIS Toric II (ZCU): Using TECNIS Toric II (ZCU) intraocular lens during standard phacoemulsification cataract surgery.

AcrySof IQ Toric: Using AcrySof IQ Toric intraocular lens during standard phacoemulsification cataract surgery.

AT TORBI 709M: Using the AT TORBI 709M intraocular lens during standard phacoemulsification cataract surgery.

Study summary

This prospective comparative cohort study evaluates and compares postoperative rotational stability and time-course dynamics of three commercially available toric intraocular lenses (TECNIS Toric II \[ZCU\], AcrySof IQ Toric, and AT TORBI 709M) after phacoemulsification cataract surgery. Rotation is quantified by registering postoperative retroillumination photographs to the end-of-surgery baseline using iris/scleral landmarks, with follow-up at postoperative day 1, day 3, week 1, week 2, month 1, and month 3. Associations between rotational outcomes and ocular biometric parameters are analyzed using linear mixed-effects models to inform individualized IOL selection and perioperative management.

Eligibility

Sex
ALL
Min age
18 Years
Max age
Healthy volunteers
No
Inclusion Criteria: * Adults aged 18 years or older with age-related cataract scheduled for phacoemulsification cataract surgery. * Presence of regular corneal astigmatism requiring toric intraocular lens implantation. * Eligible for implantation of one of the three study toric intraocular lenses based on preoperative evaluation. * Ability to understand the study procedures and provide written informed consent. Exclusion Criteria: * History of prior ocular surgery in the study eye. * History of ocular trauma in the study eye. * Irregular corneal astigmatism or corneal pathology affecting reliable biometric measurement. * Intraoperative complications, including anterior capsular tear or posterior capsular rupture. * Inadequate pupillary dilation during surgery or postoperative examinations. * Evidence of zonular weakness, zonular dialysis, or lens subluxation. * Active ocular infection or inflammation. * Any other ocular or systemic condition judged by the investigator to potentially affect intraocular lens stability or study outcomes.

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Eye and ENT hospital of Fudan University Shanghai Shanghai Municipality Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07453992 on ClinicalTrials.gov ↗ ← All trials in China