Impact of Capsular Tension Ring on Intraocular Lens Position in Retinitis Pigmentosa Cataract Patients

NCT07126470 · tracked via the Priya Life Science China tracker

Sponsor

Zhongshan Ophthalmic Center, Sun Yat-sen University

Phase

Not applicable

Started

2025-08-25

Last updated

2026-04-23

Condition(s) studied

CataractRetinitis Pigmentosa (RP)

Investigational drug(s) / intervention(s)

CTR implantation

CTR implantation: Device: CTR (275001G, OPHTEC BV, Netherlands) All patients undergo uneventful phacoemulsification by a 2.2 mm temporal transparent corneal incision using Centurion Vision System (Alcon Laboratories, Fort Worth, TX, USA). After the nucleus and cortex are removed, a capsular tension ring is implanted in the capsular bag and then IOL (J\&J Tecnis DCB00) is implanted.

Study summary

This is a self-controlled randomized clinical trial to investigate the effect of capsular tension ring (CTR) implantation on intraocular lens (IOL) position in cataract patients with retinitis pigmentosa(RP). Each patient will receive CTR implantation in one eye, with the fellow eye serving as control. Postoperative outcomes, including visual acuity, IOL position, and postoperative complications will be compared between eyes.

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Inclusion Criteria: * Age ≥ 18 years. * Clinical diagnosis of retinitis pigmentosa (RP). * Bilateral cataract meeting the indications for IOL implantation. * Willingness to participate in the study and provision of signed informed consent. Exclusion Criteria: * History of intraocular surgery. * Severe zonular weakness (e.g., zonular dialysis \>90°, lens subluxation/dislocation) * Other ocular comorbidity: such as pseudoexfoliation syndrome, ocular trauma, corneal dystrophies, uveitis, etc. * Severe systemic diseases: such as severe hypertension, diabetes, heart disease, Alzheimer's, Parkinson, etc.

Primary outcome measure(s)

IOL dencentration — 3 months after surgery
Measured by anterior segment OCT (CASIA2)

Trial sites (3)

Facility	City	Region	Status
Zhongshan Ophthalmic Center, Sun Yat-sen University	Guangzhou	Guangdong	Recruiting
Shenzhen Eye Hospital	Shenzhen	Guangdong	Not Yet Recruiting
Wuhan Aier Eye Hospital	Wuhan	Hubei	Not Yet Recruiting

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Other trials for the same condition

Multicenter Study on the Use of Intraoperative OCT in the Diagnosis and Management of Lens Diseases Active, not recruiting

Visual Quality of Cataract Patients with High Myopia After Implantation of Different Intraocular Lenses Active, not recruiting

Postoperative Rotational Dynamics of Three Toric Intraocular Lens Designs Recruiting

Comparison of Early Postoperative Visual Acuity Between Intracapsular and Supracapsular Phacoemulsification: A Randomized Controlled Clinical Trial Starting soon

D615L vs Zeiss 839MP: Visual Quality Active, not recruiting

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07126470 on ClinicalTrials.gov ↗ ← All trials in China