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Clinical Trials in Canada / NCT07317895
Starting soon Observational

Sensitivity to Ovarian Hormones and Depression in Adolescents

NCT07317895 · tracked via the Priya Life Science Canada tracker
Sponsor
University of Calgary
Phase
Observational
Started
2026-03-01
Last updated
2026-01-05

Condition(s) studied

Depressed

Study summary

The goal of this observational study is to learn about the relationship between changes in ovarian hormones (estrogen and progesterone) and adolescent depression. The main question it aims to answer is:

Can we identify a subset adolescents assigned female at birth with a history of depression who are particularly sensitive to changes in ovarian hormones? Participants will be monitoring daily absolute ovarian hormone levels at home using the Mira Analyzer and answer online survey questions about their mental health for 90 days.

Eligibility

Sex
FEMALE
Min age
12 Years
Max age
18 Years
Healthy volunteers
No
Inclusion Criteria: * Assigned female at birth, at least 1 year post-menarche, naturally cycling, history of depression or symptoms of depression, and able to read and write in English. Exclusion Criteria: * Pregnant or taking any hormonal or cycle altering medications/devices.

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
University of Calgary Calgary Alberta

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07317895 on ClinicalTrials.gov ↗ ← All trials in Canada