Respiratory muscle endurance trainingSham respiratory muscle endurance training
Respiratory muscle endurance training: Respiratory muscle endurance training program over 5 weeks.
Sham respiratory muscle endurance training: Respiratory muscle endurance training program over 5 weeks following a sham training procedure that is meant to elicit no physiologic changes.
Study summary
Respiratory muscle training (RMT) strengthens breathing muscles and may improve exercise performance and reduce breathlessness. However, different training methods and devices create controversy in the field. Two main types of RMT exist: inspiratory muscle training (IMT) and respiratory endurance training, like voluntary isocapnic hyperpnea (VIH). While IMT is well-studied, the impact of VIH on breathlessness remains unclear. This study will use the Canadian-developed BreathWayBetter device to examine how 5 weeks of VIH affects breathing discomfort and muscle function. Findings may help personalize RMT for athletes and clinical patients, improving respiratory care and exercise tolerance.
Eligibility
Sex
ALL
Min age
18 Years
Max age
55 Years
Healthy volunteers
Accepted
Inclusion Criteria:
* 18-55 years of age (inclusive)
* Male or Female (biological sex)
* Body mass index greater than 18 or less than 30 kg/m2
* Normal pulmonary function: FEV1/FVC \> 0.70 and FEV1 ≥ 80%
* Able to read and understand English
* Regularly trains and/or competes at a regional, national, or international level as a road cyclist or triathlete
* Access to a device with the capability to download the Isocapnic app (Apple IOS or Google Play/Android) or the ability to use the Web Based application.
Exclusion Criteria:
* Currently smoke, vape, or use cannabis, or have a history of frequent smoking, vaping or cannabis use
* History of, or current symptoms of cardiopulmonary (i.e., lung and/or heart) disease (excluding controlled asthma)
* Heart problem; a serious infection within the body; a neuromuscular (nerve to muscle) or musculoskeletal (muscle, ligament and/or bone) disorder; or other health problem that will be made worse with exercise testing
* Contraindications to exercise testing defined as anything that would prevent exercise under proper and safe conditions (e.g. a problem with the heart or lungs, muscle or bone injury, a serious infection)
* Currently pregnant
* Required to read and understand English due to the nature of the consent form and study materials, including questionnaires and training instructions, which are only available in English.
Primary outcome measure(s)
Change from baseline in dyspnoea ratings on the 0-10 Borg scale after respiratory endurance training — Up to 7 weeks Dyspnoea ratings on the 0-10 Borg scale will be recorded during and after incremental cardiopulmonary exercise testing on a stationary cycle ergometer. Dyspnoea ratings will then be compared between the pre- and post-intervention visits.
Difference in maximal oxygen consumption (VO2peak) following high intensity training program compared to sham comparator program. — Up to 7 weeks Changes in peak oxygen consumption (VO2peak) will be measured during an incremental cardiopulmonary exercise test on a stationary cycle ergometer and compared between intervention conditions.
Trial sites (1)
Facility
City
Region
Status
St. Paul's Hospital
Vancouver
British Columbia
Recruiting
More University of British Columbia trials in Canada
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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