Safety of ENC-201-CED ENCRT

NCT06408311 · tracked via the Priya Life Science Canada tracker

Sponsor

Encellin

Phase

Phase 1

Started

2024-05-01

Last updated

2026-03-11

Condition(s) studied

Diabetes Mellitus, Type 1

Investigational drug(s) / intervention(s)

ENC-201-CED hPI

ENC-201-CED hPI: macro-encapsulated human primary islets

Study summary

The purpose of the study is to evaluate the safety and tolerability of ENC-201-CED in a subcutaneous space in patients with Type I diabetes.

Eligibility

Sex

ALL

Min age

18 Years

Max age

70 Years

Healthy volunteers

Inclusion Criteria: * Candidates must satisfy site's eligibility for standard of care islet infusion. Exclusion Criteria: * Candidates are excluded based on the site's criteria for standard of care islet infusion.

Primary outcome measure(s)

Safety — Day 1 through Day 134
Rate of device-related Adverse Events (AE)

Trial sites (2)

Facility	City	Region	Status
UHN	Toronto	Ontario
McGill University Health Centre	Montreal	Quebec

More Encellin trials in Canada

ENCRT-103-hPI: Evaluation of an Immune-protected ENCRT-103-hPI Containing Primary Human Islets in Adults With Type 1 Diabetes, With and Without Standard-of-care Portal Vein Islet Infusion. Starting soon

Other trials for the same condition

Children's Hospital Academic Medical Organization (CHAMO) MyChart Study Active, not recruiting

Recent-Onset Type 1 Diabetes Extension Study Evaluating the Long-Term Safety of Teplizumab (PROTECT Extension) Active, not recruiting

A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type 1 Diabetes Recruiting

Support-t Online Training in Youth Living With Type 1 Diabetes Transitioning to Adult Care Recruiting

Healthy Outcomes for Muscle with Exercise in T1D Recruiting

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06408311 on ClinicalTrials.gov ↗ ← All trials in Canada