Use of Passive Myofunctional Appliances for Snoring and Mild Obstructive Sleep Apnea

NCT05497180 · tracked via the Priya Life Science Canada tracker

Sponsor

University of Alberta

Phase

Phase 1

Started

2022-07-23

Last updated

2026-09-16

Condition(s) studied

Sleep Apnea, Obstructive

Investigational drug(s) / intervention(s)

passive myofunctional appliancestandard oral appliance

passive myofunctional appliance: passive myofunctional appliance

standard oral appliance: standard oral appliance

Study summary

It is unknown whether passive myofunctional appliances can be used for the treatment of obstructive sleep apnea and snoring, nor how to select the appropriate size per individual patient. Exploring the possibility of using passive myofunctional appliances as a treatment option for patients with mild obstructive sleep apnea and/or snoring should be considered, especially as the time to fabricate and deliver custom designed dental sleep appliances can be significant (sometimes over a month). Use of passive myofunctional appliances as a transitional appliance or potentially as direct treatment for obstructive sleep apnea may significantly decrease time to treatment and also provide a less expensive treatment option for patients with obstructive sleep apnea. The purpose of this study is to determine whether passive myofunctional appliances can be used as a treatment option for patients suffering from snoring and mild obstructive sleep apnea (OSA).

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Accepted

Inclusion Criteria: * Patients diagnosed with mild obstructive sleep apnea or snoring without sleep apnea. * Patients 18 years or older * Patients able to provide consent to treatment and participation in the study Exclusion Criteria: * Patients previously diagnosed as non-responders to oral appliance therapy for their sleep apnea * Patients undergoing other active therapies for their sleep apnea * Patients with a history of airway/sleep breathing surgical interventions * Participants with a history of airway/sleep breathing surgical intervention are not eligible to be a part of this study do to risk of skewing test results * Patients with craniofacial, syndromic, or neuromuscular disorders * Patients with acute medical conditions requiring immediate attention * Participants with an acute medical problem will be immediately referred to an appropriate physician and will not be allowed to enroll in the study until their health conditions are stable.

Primary outcome measure(s)

Snoring volume — 3 months
Decibel volumetric recordings with SnoreLab app

Trial sites (1)

Facility	City	Region	Status
Enjoy Dental	Edmonton	Alberta	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05497180 on ClinicalTrials.gov ↗ ← All trials in Canada