St. Paul's Advanced Resection Center Cohort for Colorectal Neoplasia (SPARC-C)

NCT05402696 · tracked via the Priya Life Science Canada tracker

Sponsor

University of British Columbia

Phase

Observational

Started

2022-06-27

Last updated

2026-05-15

Condition(s) studied

Colon AdenomaColon PolypColon Lesion

Investigational drug(s) / intervention(s)

Endoscopic tissue resection

Endoscopic tissue resection: Endoscopic resection techniques for removal of large polyps

Study summary

The SPARC-C study is a prospective, multi-institutional observational study of patients referred for the management of large (≥ 20mm) non-pedunculated colorectal polyps (LNPCPs). Patients are managed consistent with current standards of care. Prospectively collected data includes: patient clinicodemographic details, lesion details, procedural details, and clinical outcomes.

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Inclusion Criteria: * Patients ≥ 18 years of age referred for the management of an LNPCP * Able to provide informed consent. Exclusion Criteria: * Unable to provide informed consent * Pregnant or lactating women.

Primary outcome measure(s)

Technical Success of Endoscopic Procedure — Intra-procedure
Complete removal of all visible polypoid tissue during index procedure.
Clinical Success of Endoscopic Procedure — 6 months
Technical success and the avoidance of surgery for large non-pedunculated colorectal polyps (LNPCPs) referred for endoscopic resection, assessed at first surveillance colonoscopy. LNPCPs with features consistent with invasive disease and directly referred for surgery are excluded.

Trial sites (6)

Facility	City	Region	Status
St. Cloud Hospital	Saint Cloud	Minnesota	Recruiting
Mount Saint Joseph Hospital	Vancouver	British Columbia	Active Not Recruiting
Vancouver General Hospital	Vancouver	British Columbia	Recruiting
St. Paul's Hospital	Vancouver	British Columbia	Recruiting
Pacific Gastroenterology Associates	Vancouver	British Columbia	Recruiting
Hadassah Ein Kerem Hospital	Jerusalem	Israel	Active Not Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05402696 on ClinicalTrials.gov ↗ ← All trials in Canada