Vascular Events In Patients Undergoing Same-day Noncardiac Surgery (VALIANCE) Study

NCT04973397 · tracked via the Priya Life Science Canada tracker

Sponsor

Centre hospitalier de l'Université de Montréal (CHUM)

Phase

Observational

Started

2021-11-17

Last updated

2026-03-19

Condition(s) studied

Preoperative CareSurgery--ComplicationsMyocardial Infarction

Study summary

The proportion of noncardiac surgeries performed as same-day surgery is increasing worldwide, with more complex surgeries being performed on higher risk patients in the outpatient setting. Little is known on the risk factors, incidence and prognosis of patients undergoing same-day noncardiac surgery. The main objective of this study is to inform on the incidence and risk factors of cardiovascular and other adverse events after same-day surgery and to develop risk prediction tools to better inform on the risk and selection of patients undergoing same-day surgery.

Eligibility

Sex

ALL

Min age

45 Years

Max age

—

Healthy volunteers

Inclusion Criteria: * 45-64 years of age with at least one risk factor, or ≥65 years of age; * undergoing elective noncardiac same-day surgery; * planned duration in the operating room 60 minutes or more; * provided written consent. Exclusion Criteria: * intervention does not require the presence of an anesthesiologist; * procedure is performed by a nonsurgical specialty (e.g., gastroenterology, pneumology, radio-oncology or radiology); * intervention is an ophthalmologic procedure; * previously enrolled in the VALIANCE study.

Primary outcome measure(s)

Unplanned healthcare utilization — 90 days
the number of patients who have at least one of the following: unplanned admission after surgery, unplanned outpatient visit, emergency room visit and rehospitalization after same-day surgery

Trial sites (16)

Facility	City	Region	Status
Wake Forest Baptist Medical Centre	Winston-Salem	North Carolina	Recruiting
Cleveland Clinic Foundation Fairview Campus	Cleveland	Ohio	Recruiting
Cleveland Clinic Foundation Main Campus	Cleveland	Ohio	Recruiting
MD Anderson Cancer Center	Houston	Texas	Recruiting
Memorial Hermann Texas Medical Center UT Health	Houston	Texas	Recruiting
St-Joseph's Healthcare Hamilton	Hamilton	Ontario	Active Not Recruiting
Hamilton General Hospital	Hamilton	Ontario	Recruiting
Juravinski Hospital and Cancer Centre	Hamilton	Ontario	Recruiting
McMaster University Medical Centre	Hamilton	Ontario	Recruiting
Mount Sinai Hospital	Toronto	Ontario	Recruiting
Toronto Western Hospital	Toronto	Ontario	Recruiting
St-Micheal's Hospital	Toronto	Ontario	Recruiting
Centre Hospitalier de l'Université de Montréal (CHUM)	Montreal	Quebec	Recruiting
Centre Hospitalier Universitaire de Sherbrooke	Sherbrooke	Quebec	Active Not Recruiting
Maasstad Ziekenhuis Rotterdam	Rotterdam	Netherlands	Recruiting
Hospital Clinic Barcelona	Barcelona	Spain	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT04973397 on ClinicalTrials.gov ↗ ← All trials in Canada