Optical Coherence tomography angiography: All subjects will have OCT angiography imaging performed
Study summary
Current methods of detecting glaucoma and monitoring its progression over time involve visual assessment of the optic nerve, thickness measurements of nerve tissue in the eye (using optical coherence tomography, OCT) as well as functional tests which measure peripheral, or side, vision. The objective of this study is to determine if a new technique of measuring blood flow in the eye, using OCT, can be used to better detect and/or monitor changes in glaucoma patients and suspects than these methods.
Eligibility
Sex
ALL
Min age
—
Max age
—
Healthy volunteers
Accepted
Glaucoma Group
Inclusion Criteria:
* visual acuity ≥ 6/12
* glaucomatous ONH change
* glaucomatous visual field loss with a positive Glaucoma Hemifield Test
Exclusion Criteria:
* non-glaucomatous ocular disease
* chronic systemic disease or treatment affecting the visual field
* refraction exceeding 6 D equivalent sphere or 3 D astigmatism
* inability to provide informed consent
Control Group
Inclusion Criteria:
* visual acuity ≥ 6/12
* normal eye examination with intraocular pressure ≤ 21 mm Hg
* normal visual field and negative Glaucoma Hemifield Test
Exclusion Criteria:
* chronic ocular disease
* chronic systemic disease or treatment affecting the visual field
* refraction exceeding 6 D equivalent sphere or 3 D astigmatism
* inability to provide informed consent
Primary outcome measure(s)
Blood flow — Changes over the 5 year course of the study Establish whether blood flow changes occur and if there are differences in the groups.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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