Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry

NCT02418442 · tracked via the Priya Life Science Canada tracker

Sponsor

Duke University

Phase

Observational

Started

2015-07

Last updated

2026-08-27

Condition(s) studied

Rheumatic Joint Disease

Study summary

Continuation of the CARRA Registry as described in the protocol will support data collection on patients with pediatric-onset rheumatic diseases. The CARRA Registry will form the basis for future CARRA studies. In particular, this observational registry will be used to answer pressing questions about therapeutics used to treat pediatric rheumatic diseases, including safety questions.

Eligibility

Sex

ALL

Min age

—

Max age

21 Years

Healthy volunteers

Inclusion Criteria: 1. Onset of rheumatic disease prior to age 16 years for JIA and onset prior to age 19 years for all other rheumatic diseases (see appendix A). 2. Subject (and/or parent/legal guardian when required) is able to provide written informed consent and willing to comply with study procedures. 3. Subject and/or parent/legal guardian is willing to be contacted in the future by study staff. Exclusion Criteria: 1\. Greater than 21 years of age at the time of enrollment.

Primary outcome measure(s)

Prospectively collect essential data elements from children, adolescents and young adults with pediatric rheumatic diseases — Approximately 10 years
Evaluate the safety of therapeutic agents in persons with pediatric onset rheumatic diseases — Approximately 10 years

Trial sites (82)

Facility	City	Region	Status
University of Alabama at Birmingham	Birmingham	Alabama	Recruiting
Phoenix Children's Hospital	Phoenix	Arizona	Recruiting
Children's Hospital of Los Angeles	Los Angeles	California	Not Yet Recruiting
Mattel Children's Hospital at University of California Los Angeles	Los Angeles	California	Recruiting
Stanford University Medical Center	Palo Alto	California	Recruiting
Rady Children's Hospital San Diego	San Diego	California	Recruiting
University of California at San Francisco Medical Center	San Francisco	California	Recruiting
The Children's Hospital of Colorado	Aurora	Colorado	Recruiting
Connecticut Children's Medical Center	Hartford	Connecticut	Recruiting
Yale University	New Haven	Connecticut	Terminated
Childrens National Medical Center	Washington D.C.	District of Columbia	Recruiting
University of Florida - Shand's Children's Hospital	Gainesville	Florida	Recruiting
Nicklaus Children's Hospital	Miami	Florida	Terminated
Nemours Children's Hospital	Orlando	Florida	Recruiting
Johns Hopkins All Children's Hospital	St. Petersburg	Florida	Recruiting
Emory Children's Center	Atlanta	Georgia	Recruiting
Georgia Regents University Medical Center	Augusta	Georgia	Recruiting
University of Illinois at Chicago	Chicago	Illinois	Withdrawn
Ann & Robert H. Lurie Children's Hospital of Chicago	Chicago	Illinois	Recruiting
University of Chicago Medical Center	Chicago	Illinois	Recruiting
Indiana University School of Medicine	Indianapolis	Indiana	Recruiting
The University of Iowa Hospitals and Clinics (University of Iowa Children's Hospital)	Iowa City	Iowa	Recruiting
University of Kansas Medical Center	Kansas City	Kansas	Terminated
University of Louisville Schoole of Medicine	Louisville	Kentucky	Recruiting
Tufts Medical Center	Boston	Massachusetts	Recruiting
Massachusetts General Hospital for Children	Boston	Massachusetts	Recruiting
Boston Children's Hospital	Boston	Massachusetts	Recruiting
Bay State Medical Center	Springfield	Massachusetts	Terminated
University of Michigan	Ann Arbor	Michigan	Recruiting
Helen Devos Children's Hospital	Grand Rapids	Michigan	Recruiting
West Michigan Rheumatology	Grand Rapids	Michigan	Terminated
University of Minnesota	Minneapolis	Minnesota	Recruiting
Mayo Clinic	Rochester	Minnesota	Recruiting
University of Mississippi Medical Center	Jackson	Mississippi	Recruiting
Children's Mercy Hospital	Kansas City	Missouri	Recruiting
Saint Louis University School of Medicine	St Louis	Missouri	Terminated
Saint Louis Children's Hospital	St Louis	Missouri	Recruiting
Hackensack University Medical Center	Hackensack	New Jersey	Recruiting
Goryeb Children's Hospital	Morristown	New Jersey	Recruiting
Robert Wood Johnson Medical School	New Brunswick	New Jersey	Recruiting

+ 42 more sites — see the full list on the official registry below.

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT02418442 on ClinicalTrials.gov ↗ ← All trials in Canada