n-3 PUFA supplementation: 3g per day of n-3 PUFA supplementation (1.9g EPA, 1.1g DHA). 5 capsules per day (1g fish oil each, 5g of fish oil/day)
Study summary
The main purpose of this study is to examine whether n-3 PUFA-induced changes in metabolic risk factors are influenced by genetic variations within genes acting as fatty acids sensors.
Eligibility
Sex
ALL
Min age
18 Years
Max age
50 Years
Healthy volunteers
Accepted
Inclusion Criteria:
* healthy men and women aged between 18 to 50 years;
* having a BMI between 25 and 40kg/m2;
* plasma triglycerides levels \<4.0 mmol/L;
* non-smokers;
* free of any thyroid or metabolic disorders requiring treatment such as diabetes, hypertension, severe dyslipidemia, and coronary heart disease.
Exclusion Criteria:
* subjects taking medication for hyperlipidemia, hypertension, diabetes or taking anticoagulant or n-3 PUFA supplementation;
* having a taste aversion for fish, fish allergy or regular alcohol drinker;
* body mass index \> 40kg/m2;
* pregnant or nursing women.
Primary outcome measure(s)
Change in blood lipids (Total cholesterol, HDL-Cholesterol, Triglycerides) — Before and after a 6-weeks supplementation
Trial sites (1)
Facility
City
Region
Status
Institute of Nutraceutical and Functional Foods (INAF), Laval University
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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