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Clinical Trials in Belgium / NCT05460416
Recruiting Phase 3

Treatment Preventive for Pre-eclampsia by Acetylsalicylic Acid in Women Who Underwent Frozen Embryo Transfer

NCT05460416 · tracked via the Priya Life Science Belgium tracker
Phase
Phase 3
Started
2022-10-25
Last updated
2025-02-18

Condition(s) studied

Embryo TransferHypertension, Pregnancy Induced

Investigational drug(s) / intervention(s)

Acetylsalicylic acid →

Acetylsalicylic acid: 160mg once a day

Study summary

Title: A prospective multicentric interventional randomized controlled trial to assess the effect of low dose acetylsalicylic acid as a preventive treatment of pre-eclampsia in pregnant women who underwent frozen embryo transfer

Eligibility

Sex
FEMALE
Min age
18 Years
Max age
43 Years
Healthy volunteers
No
Inclusion Criteria: * Healthy women from \[18 - 43\] years-old, planned for a frozen embryo transfer, with natural and modified natural or HRT cycle * Who have given their informed consent * Who have a confirmed pregnancy at week 6 of amenorrhea. Exclusion Criteria: * Women presenting one risk factor for preeclampsia: multiple pregnancy, history of preeclampsia, BMI \> 30, lupus syndrome, preexistent proteinuria, non-treated chronic high blood pressure (\>140/90), antiphospholipid antibody syndrome, diabetes (fasting blood sugar \>126mg/dl) * Contraindication to acetylsalicylic acid (at risk of active hemorrhage (like hemophilia, …); at risk of or who have a gastro-duodenal ulcer; at risk or how have a terminal renal or hepatic in-sufficiency (only if acetylsalicylic acid is given at high dose) * Already treated with acetylsalicylic acid * Treatment with anticoagulants or non-steroid anti-inflammatory drugs

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Centre Hospitalier Universitaire de Liège site Citadelle Liège Belgium Recruiting

More Centre Hospitalier Universitaire de Liege trials in Belgium

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05460416 on ClinicalTrials.gov ↗ ← All trials in Belgium