Title: A prospective multicentric interventional randomized controlled trial to assess the effect of low dose acetylsalicylic acid as a preventive treatment of pre-eclampsia in pregnant women who underwent frozen embryo transfer
Eligibility
Sex
FEMALE
Min age
18 Years
Max age
43 Years
Healthy volunteers
No
Inclusion Criteria:
* Healthy women from \[18 - 43\] years-old, planned for a frozen embryo transfer, with natural and modified natural or HRT cycle
* Who have given their informed consent
* Who have a confirmed pregnancy at week 6 of amenorrhea.
Exclusion Criteria:
* Women presenting one risk factor for preeclampsia: multiple pregnancy, history of preeclampsia, BMI \> 30, lupus syndrome, preexistent proteinuria, non-treated chronic high blood pressure (\>140/90), antiphospholipid antibody syndrome, diabetes (fasting blood sugar \>126mg/dl)
* Contraindication to acetylsalicylic acid (at risk of active hemorrhage (like hemophilia, …); at risk of or who have a gastro-duodenal ulcer; at risk or how have a terminal renal or hepatic in-sufficiency (only if acetylsalicylic acid is given at high dose)
* Already treated with acetylsalicylic acid
* Treatment with anticoagulants or non-steroid anti-inflammatory drugs
Primary outcome measure(s)
Mean number of women suffering from pre-eclampsia in the treated and not treated groups. — 4 years
Trial sites (1)
Facility
City
Region
Status
Centre Hospitalier Universitaire de Liège site Citadelle
Liège
Belgium
Recruiting
More Centre Hospitalier Universitaire de Liege trials in Belgium
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
We use cookies to analyse site traffic and improve your experience. With your consent, we may also use cookies for advertising. You can change your choice at any time.