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Clinical Trials in Australia / NCT07478952
Recruiting Phase 1

A Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1189 in Healthy Adults 18 to 30 Years of Age

NCT07478952 · tracked via the Priya Life Science Australia tracker
Phase
Phase 1
Started
2026-03-17
Last updated
2026-03-24

Condition(s) studied

Epstein-Barr Virus

Investigational drug(s) / intervention(s)

mRNA-1189 →

mRNA-1189: Sterile liquid for injection

Study summary

The main objective of this trial is to evaluate the safety and immunogenicity of mRNA-1189 after intradermal and intramuscular delivery.

Eligibility

Sex
ALL
Min age
18 Years
Max age
30 Years
Healthy volunteers
Accepted
Inclusion Criteria: * Healthy as determined by medical evaluation including medical history and physical examination. * Participants who are assigned female at birth or could become pregnant are eligible to participate if the participant is not pregnant or breast/chest feeding. Exclusion Criteria: * Have undergone surgical procedures within 7 days prior to Day 1 or Day 57 or are scheduled to undergo a surgical procedure within 28 days after study intervention administration. * Reported history of congenital or acquired immunodeficiency, immunosuppressive condition, asplenia, or recurrent severe infectious disease. * Received corticosteroids at ≥10 milligrams per day (mg/day) of prednisone or equivalent for \>14 days in total within 90 days prior to Day 1 or is anticipating the need for corticosteroids at any time during the study. * Received systemic immunosuppressive treatment, including long-acting biological therapies that affect immune responses, within 180 days prior to Day 1 or plans to do so during the study. * Received or plans to receive any nonstudy vaccine from 28 days prior to first dose/Day 1 up to 28 days after the second dose/Day 57. * History of myocarditis, pericarditis, or myopericarditis prior to Day 1. * Has previously received an investigational EBV vaccine. Note: Other inclusion and exclusion criteria may apply.

Primary outcome measure(s)

Trial sites (2)

FacilityCityRegionStatus
Nucleus Network Melbourne Victoria Recruiting
Doherty Clinical Trials Melbourne Victoria Not Yet Recruiting

More ModernaTX, Inc. trials in Australia

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07478952 on ClinicalTrials.gov ↗ ← All trials in Australia