Active (Green tea and caffeine): Two 355 mL cans of "XS Energy + BURN" drink containing caffeine and green tea extract.
Placebo: Two 355 mL cans of placebo drink but without the active ingredients (caffeine and green tea extract).
Study summary
The goal of this study is to evaluate the influence of consuming a drink containing a combination of caffeine and green tea extracts on fat oxidation responses at rest, during and after a period of endurance type exercise.
Eligibility
Sex
ALL
Min age
18 Years
Max age
45 Years
Healthy volunteers
Accepted
Inclusion Criteria:
* Passing the Exercise and Sport Science Australia adult pre-exercise screening system (APSS) stage 1 \& 2 (see appendix 4).
* Between the ages of 18 and 45,
* Not sedentary, and not completing more than 150 minutes of low and/or moderate and/or or vigorous intensity endurance exercise a week,
* Ability to commit to in principle fulfilment of all 3 trial visits,
* No history of coagulopathy e.g., DVT, stroke,
* No known heart disease,
* No known pancreatic insufficiency,
* No known inflammatory bowel disease, or prior bowel resection or bypass surgery (excluding gastric banding and sleeve),
* BMI of 22.0 to 34.9 kg/m2,
* No known allergies to caffeine or green tea extract,
* No known type I or II diabetes,
* No uncontrolled concurrent illness,
* No known current pregnancy or breastfeeding women
* No current regular consumption of supplements (\>2 times a week) or foods and drinks containing caffeine and/or green tea extracts (\>2 times per day, weekly).
* Agree not to consume caffeine for 12-hours prior to the clinic visit.
Exclusion Criteria:
* Triggering any of the exclusion screening criteria as outlined below, and in compliment with the Exercise and Sport Science Australia adult pre-exercise screening system (APSS).
* Under the age of 18 or over the age of 45,
* Sedentary, or completing over 150 minutes of low and/or moderate and/or or vigorous intensity endurance exercise a week,
* Inability to commit to in principle fulfilment of all 3 trial visits,
* History of coagulopathy e.g., DVT, stroke,
* Known heart disease,
* Known pancreatic insufficiency,
* Known inflammatory bowel disease, or prior bowel resection or bypass surgery (excluding gastric banding and sleeve),
* BMI \< 22.0 or \> 34.9 kg/m2,
* Known allergies to caffeine or green tea extract,
* Known type I or II diabetes,
* Uncontrolled concurrent illness,
* Taking GLP-1 agonists, caffeine, or any other medication known to affect metabolism.
* Known current pregnancy or breastfeeding women.
* Currently regularly consuming supplements, foods or drinks containing a caffeine and green tea extract blend, or not willing to abstain for the study
Primary outcome measure(s)
Fat oxidation as measured by indirect calorimetry — Baseline to 30 mins post exercise Change from baseline to the end of the study period in Fat oxidation as measured by indirect calorimetry (metabolic cart); baseline (pre-drink), post-drink (pre-exercise), time sequence e.g., every 5-min during exercise, 10, 20 and 30-min post-exercise. Change from baseline \& total. Fat oxidation will be measured continuously throughout the exercise and the 30-min post-exercise window, to facilitate total, and any other temporal fat oxidation timepoints.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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