Total intravenous anesthesia (TIVA)Sevoflurane initiated intravenous anesthesia (SIIVA)
Total intravenous anesthesia (TIVA): TIVA anesthetic -no inhalational gases for surgery
Sevoflurane initiated intravenous anesthesia (SIIVA): SIIVA - sevoflurane anesthetic gases for surgery
Study summary
Because Propofol is the primary "anesthetic agent," and inhalational agents remain in trace quantities at the end of the procedure Sevoflurane initiated intravenous anesthesia (SIIVA) or not present at all Total intravenous anesthesia (TIVA) it is likely that different criteria may be predictive of extubation success in these patients compared to inhalational anesthesia.
Eligibility
Sex
ALL
Min age
—
Max age
9 Years
Healthy volunteers
No
Inclusion Criteria:
* Pediatric patients \<10 years of age
* Undergoing elective or emergency surgery with planned airway instrumentation with an endotracheal tube (ETT)
* Patients having general anesthesia with a planned SIIVA or TIVA technique
* Patients with an end tidal agent concentration of Sevoflurane\<0.1% at the time of emergence and extubation
* following sevoflurane induction to place IV
Exclusion Criteria:
* History of home oxygen use or ventilator dependence
* Patients with cyanotic congenital heart disease
* Patients undergoing anesthesia for imaging procedures alone
* Patients intended to be managed with supraglottic airway
* Patients having an anesthesia time \< 30 minutes
* Monitored Anesthesia Care (not general anesthesia)
* Patients with contraindication to receiving Propofol (i.e. mitochondrial myopathy)
Primary outcome measure(s)
Extubation success rate — Day 1 quality of extubation will be assess using a standard rubric for all extubation
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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