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Verve Therapeutics clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — current trials in our UK and USA registers with Verve Therapeutics as lead sponsor. Synced 26 Sep 2026
4Current trials
2Recruiting now
1Drug in these trials
2Trial registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 — Top 14 finalist
Compiled from ClinicalTrials.gov and CTIS registry records · Last verified · Editorial standards
At a glance

Verve Therapeutics is the lead sponsor of 4 current clinical trials in our UK and USA registers. 2 are recruiting patients now. The most common phase is Phase 1. The drugs named most often in its trials are VERVE-102. The most-studied condition is Hypercholesterolemia.

ClinicalTrials.gov trials by status

  • Recruiting250%
  • Not yet open125%
  • By invitation125%

Trials by phase

  • Phase 1250%
  • Observational125%
  • Phase 2125%
01

Clinical trials sponsored by Verve Therapeutics

4 on ClinicalTrials.gov
StudyPhaseStatusStartRegisters
Phase 1b Study of VERVE-201 in Patients With Refractory Hyperlipidemia
NCT06451770 · ClinicalTrials.gov ↗ · Hypercholesterolemia, Hypertriglyceridemia, Refractory Hyperlipidemia
Phase 1 Recruiting 2024-10 UK, USA
A Study of VERVE-102 in Patients With Familial Hypercholesterolemia or Premature Coronary Artery Disease
NCT06164730 · ClinicalTrials.gov ↗ · Heterozygous Familial Hypercholesterolemia, Premature Coronary Heart Disease
Drug: VERVE-102
Phase 1 Recruiting 2024-04 UK, USA
A Study of VERVE-102 (LY4636581) in Adults With or at High Risk for Cardiovascular Disease
NCT07839936 · ClinicalTrials.gov ↗ · Atherosclerosis, Cardiovascular Disease, Hypercholesterolemia
Drug: VERVE-102
Phase 2 Not yet open 2026-10 USA
Long-term Follow-up of Participants Dosed With an Investigational Gene Editing Therapy for Cardiovascular Disease
NCT06112327 · ClinicalTrials.gov ↗ · Atherosclerotic Cardiovascular Disease, Heterozygous Familial Hypercholesterolemia, Hypercholesterolemia
Observational By invitation 2024-06 UK

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Titles and statuses are copied from the registry as published.

02

Drugs in Verve Therapeutics trials

1 compound

Drugs and biologicals named as interventions in these trials, with the number of this sponsor's trials that name each one. Placebos and generic comparators are excluded.

03

Conditions in Verve Therapeutics trials

8 conditions
Hypercholesterolemia3Heterozygous Familial Hypercholesterolemia2Hypertriglyceridemia1Refractory Hyperlipidemia1Premature Coronary Heart Disease1Atherosclerotic Cardiovascular Disease1Atherosclerosis1Cardiovascular Disease1
04

By trial register

RegisterTrialsRecruiting
Clinical trials in UK32
Clinical trials in USA32

A trial with sites in more than one country appears in each of those registers.

05

Questions about Verve Therapeutics trials

How many clinical trials does Verve Therapeutics sponsor?

Verve Therapeutics is the lead sponsor of 4 current trials on ClinicalTrials.gov in our UK and USA registers, as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.

Are Verve Therapeutics trials recruiting?

Yes. 2 of its 4 ClinicalTrials.gov trials are recruiting. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Which drugs is Verve Therapeutics testing?

Its current trials name 1 drug or biological as interventions. The most frequent are VERVE-102 (2). The number in brackets is how many of its trials name each drug.

Where does this information come from?

Every trial, status, phase and condition on this page is copied from public ClinicalTrials.gov and EU CTIS records by a daily sync, grouped by the sponsor name each registry records. It says nothing about the organisation beyond its registered trials, and it is not medical advice.

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How this page is built

Everything on this page is copied from public registry records — it is not written from memory, and nothing here describes the organisation beyond its registered trials. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our trial registers and groups every current trial by its lead sponsor name, ignoring legal-form suffixes such as Inc. or Ltd. A small, hand-checked list joins the same organisation's different registry names (for example its EU legal entity). There is no AI drafting and no per-sponsor editorial pass. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The the registries data on this page was last retrieved on 26 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.